Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 18/20 | 0.68 |
| ▸ | IDO1 | P14902 | 17/20 | 0.68 |
| ▸ | IDO2 | Q6ZQW0 | 15/20 | 0.68 |
| ▸ | APAF1 | O14727 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18133819 | 0.83 | TDO2 (0.80) | TDO2IDO1IDO2APAF1NPC1 | |
| SCHEMBL26857025 | 0.81 | TDO2 (0.68) | TDO2IDO1IDO2APAF1NPC1 | |
| SCHEMBL18059863 | 0.81 | TDO2 (1.00) | TDO2IDO1IDO2APAF1NPC1 | |
| SCHEMBL30639082 | 0.81 | TDO2 (1.00) | TDO2IDO1IDO2APAF1NPC1 | |
| SCHEMBL26856831 | 0.81 | TDO2 (0.77) | TDO2IDO1IDO2APAF1NPC1 | |
| SCHEMBL26614219 | 0.80 | IDO1 (0.64) | TDO2IDO1IDO2APAF1NPC1 | |
| SCHEMBL25302415 | 0.69 | TDO2 (0.69) | TDO2IDO1IDO2APAF1NPC1 | |
| SCHEMBL31382861 | 0.69 | IDO1 (0.77) | TDO2IDO1IDO2APAF1NPC1 | |
| SCHEMBL30639081 | 0.69 | IDO1 (0.78) | TDO2IDO1IDO2APAF1NPC1 | |
| SCHEMBL26614148 | 0.69 | IDO1 (0.77) | TDO2IDO1IDO2APAF1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023211977-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | VISCIENT BIO, INC. (US) | 2023-11-02 | — | — | WO | disclosed |