Parathion

Parathion

SCHEMBL26857

CCOP(=S)(OCC)Oc1ccc([N+](=O)[O-])cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 1.00
CYP3A4 P08684 2/20 1.00
MAPK1 P28482 2/20 1.00
HSD17B10 Q99714 2/20 1.00
TSHR P16473 1/20 1.00
CA1 P00915 2/20 0.69
CA2 P00918 2/20 0.69
BCHE P06276 1/20 0.69
ACHE P22303 1/20 0.69
LMNA P02545 1/20 0.69
TP53 P04637 1/20 0.69
THRB P10828 1/20 0.69
SMN1; SMN2 Q16637 1/20 0.69
CES2 O00748 1/20 0.51
CES1 P23141 1/20 0.51
BCL9 O00512 1/20 0.49
CTNNB1 P35222 1/20 0.49
PTGS2 P35354 1/20 0.49
HSPB1 P04792 1/20 0.45
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Parathion SCHEMBL10447034 0.98 ALDH1A1 (0.97) ALDH1A1CYP3A4MAPK1HSD17B10TSHR
Parathion SCHEMBL17981469 0.98 ALDH1A1 (0.97) ALDH1A1CYP3A4MAPK1HSD17B10TSHR
Parathion SCHEMBL8779525 0.98 ALDH1A1 (0.97) ALDH1A1CYP3A4MAPK1HSD17B10TSHR
Parathion SCHEMBL20271121 0.98 ALDH1A1 (0.97) ALDH1A1CYP3A4MAPK1HSD17B10TSHR
Parathion SCHEMBL8960276 0.98 ALDH1A1 (0.97) ALDH1A1CYP3A4MAPK1HSD17B10TSHR
Parathion SCHEMBL10447032 0.98 ALDH1A1 (0.97) ALDH1A1CYP3A4MAPK1HSD17B10TSHR
Parathion SCHEMBL8960270 0.98 ALDH1A1 (0.97) ALDH1A1CYP3A4MAPK1HSD17B10TSHR
Parathion SCHEMBL10585964 0.98 ALDH1A1 (0.97) ALDH1A1CYP3A4MAPK1HSD17B10TSHR
Parathion SCHEMBL10436147 0.98 ALDH1A1 (0.97) ALDH1A1CYP3A4MAPK1HSD17B10TSHR
Parathion SCHEMBL10585960 0.98 ALDH1A1 (0.97) ALDH1A1CYP3A4MAPK1HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 32049 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2026-05-21 US claimed
US-20260130877-A1 TREATMENT OF NEURODEVELOPMENTAL DISORDERS THE REGENTS OF THE UNIV OF CALIFORNIA (US) 2026-05-14 US claimed
CN-122016741-A Method for detecting coumaphos based on carbon quantum dot-ferric ion solution system 河南医药大学 2026-05-12 CN claimed
EP-4734763-A1 COMPOSITIONS, METHODS AND DEVICES FOR CONTROL AND MONITORING INSECTS Agriculture Victoria Services Pty Ltd (AU) 2026-05-06 EP claimed
EP-4734762-A1 BAIT COMPOSITIONS FMC Corporation (US) 2026-05-06 EP claimed
US-20260114446-A1 Compositions, Methods and Devices for Control and Monitoring Insects AGRICULTURE VICTORIA SERVICES PTY LTD (AU) 2026-04-30 US claimed
EP-4723893-A2 COMPOSITIONS AND METHODS TO MITIGATE PHYTOTOXIC EFFECTS OF AGRICHEMICALS Ascribe Bioscience Inc. (US) 2026-04-15 EP claimed
EP-4719059-A1 INCREASED PALATABILITY OF INSECTICIDAL INSECT BAITS Bio Logic Crop Science, S.L. (ES) 2026-04-08 EP claimed
US-20260083130-A1 NOVEL SULFONATE BENZAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS FMC CORP (US) 2026-03-26 US claimed
US-20260083129-A1 PYRAZOLE AMIDE INSECTICIDES FMC CORP (US) 2026-03-26 US claimed
EP-0068297-A1 A new insecticidal composition, processes for its production and its use A. Nattermann & Cie. GmbH (DE) 1983-01-05 EP claimed
US-4353962-A USING AN ACRYLIC POLYMER ENVIRONMENTAL CHEMICALS, INC. (US) 1982-10-12 US claimed
EP-0008207-B1 INSECTICIDAL COMPOSITIONS, AND PREPARATION AND USE THEREOF E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-12-02 EP claimed
EP-0005310-B1 PROCESS FOR PREPARING DIALKYLPHOSPHOROCHLORIDOTHIOATES, THE USE OF THE SO PREPARED COMPOUNDS AS INTERMEDIATES, AND THE USE OF SOME OF THE FINAL PRODUCTS AS INSECTICIDES ETHYL CORPORATION (US) 1981-09-30 EP claimed
US-4291497-A Method of introducing chemical agents into plants MANANKOV MIKHAIL K 1981-09-29 US claimed
US-4286020-A BY SPRAYING A FILM FORMING POLYMER OF POLYVINYL ACETATE, POLYVINYL ETHER OR AN ACRYLIC POLYMER ENVIRONMENTAL CHEMICALS, INC. (US) 1981-08-25 US claimed
EP-0008207-A2 Insecticidal compositions, and preparation and use thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 1980-02-20 EP claimed
EP-0005310-A1 Process for preparing dialkylphosphorochloridothioates, the use of the so prepared compounds as intermediates, and the use of some of the final products as insecticides ETHYL CORPORATION (US) 1979-11-14 EP claimed
US-4103450-A LOW DENSITY WEB IMPREGNATED WITH INSECTICIDE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-08-01 US claimed
US-3959464-A Microencapsulated methyl and ethyl parathion insecticide in aqueous carrier PENNWALT CORPORATION (US) 1976-05-25 US claimed