⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL791682 | 0.69 | NQO1 (0.50) | — | |
| SCHEMBL3559683 | 0.68 | — | — | |
| SCHEMBL8453468 | 0.66 | NQO1 (0.47) | — | |
| SCHEMBL27509036 | 0.65 | BCHE (0.32) | — | |
| SCHEMBL2041141 | 0.64 | — | — | |
| SCHEMBL2177755 | 0.62 | — | — | |
| SCHEMBL11223894 | 0.62 | — | — | |
| SCHEMBL7401829 | 0.61 | — | — | |
| SCHEMBL921713 | 0.60 | SOS1 (0.36) | — | |
| SCHEMBL317653 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008098859-A1 | HCV POLYMERASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-08-21 | — | — | WO | claimed |
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | BLANEY JEFFREY MARK | 2008-08-21 | — | — | US | claimed |
| EP-3093286-B1 | THIAZOLE COMPOUNDS AND PEST CONTROL APPLICATIONS THEREOF | SUMITOMO CHEMICAL CO (JP) | 2019-07-10 | — | — | EP | disclosed |
| EP-2586827-B1 | CURABLE RESIN COMPOSITION | ADEKA CORP (JP) | 2017-12-27 | — | — | EP | disclosed |
| US-9730449-B2 | Thiazole compound and its use in pest control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-15 | — | — | US | disclosed |
| EP-3093286-A1 | THIAZOLE COMPOUNDS AND PEST CONTROL APPLICATIONS THEREOF | Sumitomo Chemical Co., Ltd (JP) | 2016-11-16 | — | — | EP | disclosed |
| US-20160324155-A1 | THIAZOLE COMPOUND AND ITS USE IN PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-11-10 | — | — | US | disclosed |
| US-8735511-B2 | Curing resin composition | ADEKA CORPORATION (JP) | 2014-05-27 | — | — | US | disclosed |
| EP-2586827-A1 | CURABLE RESIN COMPOSITION | Adeka Corporation (JP) | 2013-05-01 | — | — | EP | disclosed |
| US-20120115972-A1 | CURING RESIN COMPOSITION | ADEKA CORPORATION (JP) | 2012-05-10 | — | — | US | disclosed |
| WO-2008098859-A1 | HCV POLYMERASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-08-21 | — | — | WO | disclosed |
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | BLANEY JEFFREY MARK | 2008-08-21 | — | — | US | disclosed |
| CN-1723199-A | 1,4-disubstituted piperidine derivatives and their use as 11-beta hsd1 inhibitors | ASTRAZENECA AB (SE) | 2006-01-18 | — | — | CN | disclosed |