Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8453468 | 0.83 | NQO1 (0.47) | NQO1NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL790619 | 0.81 | RAB9A (0.50) | NPC1RAB9APOLBSMN1; SMN2MAPK1 | |
| SCHEMBL317653 | 0.72 | — | — | |
| 1,4-Diethoxybenzene SCHEMBL124015 | 0.71 | NQO1 (1.00) | NQO1NPC1POLBSMN1; SMN2TDP1 | |
| 1,4-Diethoxybenzene SCHEMBL28186701 | 0.71 | NQO1 (1.00) | NQO1NPC1POLBSMN1; SMN2TDP1 | |
| SCHEMBL2686178 | 0.69 | — | — | |
| 1,4-Diethoxybenzene SCHEMBL11794798 | 0.68 | NQO1 (0.93) | NQO1NPC1POLBSMN1; SMN2TDP1 | |
| SCHEMBL92159 | 0.67 | NQO1 (0.78) | NQO1SMN1; SMN2TDP1LTA4HTSHR | |
| 1,4-Diethoxybenzene SCHEMBL27616183 | 0.66 | NQO1 (0.88) | NQO1NPC1SMN1; SMN2TDP1MAPT | |
| 1-Hydroxy-4-Ethoxybenzene SCHEMBL28520 | 0.65 | LTA4H (0.86) | NQO1NPC1TDP1MAPTLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616459-B1 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS I | BASF SE (DE) | 2016-05-04 | — | — | EP | disclosed |
| US-8609700-B2 | Pyridine compounds for controlling invertebrate pests I | BASF SE (DE) | 2013-12-17 | — | — | US | disclosed |
| EP-2616459-A1 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS I | BASF SE (DE) | 2013-07-24 | — | — | EP | disclosed |
| US-20130178502-A1 | Pyridine Compounds for Controlling Invertebrate Pests I | BASF SE (DE) | 2013-07-11 | — | — | US | disclosed |
| WO-2012034961-A1 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS I | BASF SE (DE) | 2012-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130178502-A1 | Pyridine Compounds for Controlling Invertebrate Pests I | GRIN2A, PRXL2A, MT-CO2 | NQO1 540/4885NPC1 3099/4885RAB9A 977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.