Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 10/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 7/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 6/20 | 0.39 |
| ▸ | SRC | P12931 | 3/20 | 0.38 |
| ▸ | RAF1 | P04049 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26656443 | 0.83 | CCNA2 (0.44) | MAP2K1PDE4BEGFRERBB2SRC | |
| SCHEMBL26863121 | 0.82 | MAP2K1 (0.40) | MAP2K1PDE4BEGFRERBB2SRC | |
| SCHEMBL26864049 | 0.82 | MAP2K1 (0.40) | MAP2K1PDE4BEGFRERBB2SRC | |
| SCHEMBL26864601 | 0.81 | GAK (0.36) | EGFRERBB2 | |
| SCHEMBL26862956 | 0.81 | GAK (0.36) | EGFRERBB2 | |
| SCHEMBL26863122 | 0.77 | MAP2K1 (0.43) | MAP2K1EGFRERBB2SRCRAF1 | |
| SCHEMBL26863552 | 0.71 | GAK (0.35) | EGFR | |
| SCHEMBL24028614 | 0.68 | MAP2K1 (0.58) | MAP2K1PDE4BEGFRERBB2SRC | |
| SCHEMBL26656450 | 0.68 | CDK1 (0.45) | MAP2K1PDE4BEGFRERBB2RAF1 | |
| SCHEMBL31700843 | 0.68 | MAPT (0.38) | PDE4BSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023225001-A1 | NAPHTHYRIDINE BASED ENPP1 MODULATORS AND USES THEREOF | Vir Biotechnology, Inc. (US) | 2023-11-23 | — | — | WO | disclosed |