Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 10/20 | 0.40 |
| ▸ | EGFR | P00533 | 7/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 7/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | STK4 | Q13043 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26864049 | 1.00 | MAP2K1 (0.40) | MAP2K1EGFRERBB2PDE4BSRC | |
| SCHEMBL26865331 | 0.82 | BRAF (0.36) | — | |
| SCHEMBL30666120 | 0.82 | BRAF (0.36) | — | |
| SCHEMBL26656440 | 0.82 | BRAF (0.36) | — | |
| SCHEMBL26864188 | 0.82 | BRAF (0.36) | — | |
| SCHEMBL26863388 | 0.82 | MAP2K1 (0.40) | MAP2K1EGFRERBB2PDE4BSRC | |
| SCHEMBL26656443 | 0.81 | CCNA2 (0.44) | MAP2K1EGFRERBB2PDE4BSRC | |
| SCHEMBL26863122 | 0.75 | MAP2K1 (0.43) | MAP2K1EGFRERBB2SRCRAF1 | |
| SCHEMBL30666116 | 0.75 | BRAF (0.36) | — | |
| SCHEMBL26656465 | 0.75 | BRAF (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023225001-A1 | NAPHTHYRIDINE BASED ENPP1 MODULATORS AND USES THEREOF | Vir Biotechnology, Inc. (US) | 2023-11-23 | — | — | WO | disclosed |