SCHEMBL2686340

SCHEMBL2686340

CCCCC(=O)C1(COCC)c2ccccc2-c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MTTP P55157 1/20 0.36
APEX1 P27695 1/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
PDK2 Q15119 2/20 0.36
SOAT1 P35610 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2688778 0.96 SOAT1 (0.40) MTTPCES2CES1PDK2SOAT1
SCHEMBL2688098 0.94 SOAT1 (0.42) CES2CES1PDK2SOAT1
SCHEMBL2687830 0.94 SOAT1 (0.42) CES2CES1PDK2SOAT1
SCHEMBL2688838 0.94 SOAT1 (0.42) CES2CES1PDK2SOAT1
SCHEMBL2686958 0.91 APEX1 (0.38) APEX1PDK2
SCHEMBL2685785 0.90 MTTP (0.38) MTTPAPEX1CES2CES1PDK2
SCHEMBL2689166 0.90 PDK2 (0.40) MTTPPDK2
SCHEMBL2686335 0.89 PDK2 (0.41) MTTPPDK2
SCHEMBL2686719 0.87 APEX1 (0.37) MTTPAPEX1CES2CES1PDK2
SCHEMBL2686331 0.86 PDK2 (0.41) MTTPPDK2SOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3118226-A1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF Corporation (US) 2017-01-18 EP claimed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP claimed
EP-2782938-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF Corporation (US) 2014-10-01 EP claimed
CN-104053682-A High activity catalyst component for olefin polymerization and method of using the same BASF SE 2014-09-17 CN claimed
WO-2013077837-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF CORPORATION (US) 2013-05-30 WO claimed
US-8227370-B2 High activity catalyst component for olefin polymerization and method of using the same BASF CORPORATION (US) 2012-07-24 US claimed
US-20120116031-A1 High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same BASF CORPORATION (US) 2012-05-10 US claimed
CN-107207657-B Process for preparing spherical polymerization catalyst components for olefin polymerization 格雷斯公司 2020-03-03 CN disclosed
EP-3118226-A1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF Corporation (US) 2017-01-18 EP disclosed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP disclosed
EP-2782938-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF Corporation (US) 2014-10-01 EP disclosed
WO-2013077837-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF CORPORATION (US) 2013-05-30 WO disclosed
US-8227370-B2 High activity catalyst component for olefin polymerization and method of using the same BASF CORPORATION (US) 2012-07-24 US disclosed
US-20120116031-A1 High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same BASF CORPORATION (US) 2012-05-10 US disclosed