SCHEMBL2689166

SCHEMBL2689166

CCCCOCC1(C(=O)CCCC)c2ccccc2-c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 4/20 0.40
MTTP P55157 1/20 0.40
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TDP2 O95551 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2686331 0.96 PDK2 (0.41) PDK2MTTPTSHRTDP1L3MBTL1
SCHEMBL2686335 0.96 PDK2 (0.41) PDK2MTTPTSHRTDP1L3MBTL1
SCHEMBL2688055 0.95 PDK2 (0.42) PDK2MTTPTSHRTDP2ALDH1A1
SCHEMBL2686846 0.95 PDK2 (0.42) PDK2MTTPTSHRTDP2ALDH1A1
SCHEMBL2685876 0.95 PDK2 (0.42) PDK2MTTPTSHRTDP2ALDH1A1
SCHEMBL2685785 0.94 MTTP (0.38) PDK2MTTPCYP2C9CYP2C19NPSR1
SCHEMBL2688172 0.94 PDK2 (0.40) PDK2MTTPTSHRTDP1L3MBTL1
SCHEMBL14977678 0.93 PDK2 (0.44) PDK2TSHRTDP1L3MBTL1CYP2C9
SCHEMBL2689532 0.93 PDK2 (0.41) PDK2MTTPTSHRTDP1L3MBTL1
SCHEMBL14977552 0.92 PDK2 (0.40) PDK2MTTPTDP1L3MBTL1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104053682-B For the high activity catalyst component and its application method of olefinic polymerization 格雷斯公司 2017-05-31 CN claimed
EP-3118226-A1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF Corporation (US) 2017-01-18 EP claimed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP claimed
CN-102834420-B Internal and external donor compounds for olefin polymerization catalysts ii BASF CORP. (US) 2014-10-22 CN claimed
EP-2782938-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF Corporation (US) 2014-10-01 EP claimed
WO-2013077837-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF CORPORATION (US) 2013-05-30 WO claimed
US-8227370-B2 High activity catalyst component for olefin polymerization and method of using the same BASF CORPORATION (US) 2012-07-24 US claimed
CN-102574954-A Internal donor for olefin polymerization catalysts BASF CATALYSTS LLC 2012-07-11 CN claimed
US-20120116031-A1 High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same BASF CORPORATION (US) 2012-05-10 US claimed
CN-107207657-B Process for preparing spherical polymerization catalyst components for olefin polymerization 格雷斯公司 2020-03-03 CN disclosed
CN-107207657-A The method for preparing the spherical polymerization catalyst component for olefinic polyreaction 格雷斯公司 2017-09-26 CN disclosed
CN-104053682-B For the high activity catalyst component and its application method of olefinic polymerization 格雷斯公司 2017-05-31 CN disclosed
EP-3118226-A1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF Corporation (US) 2017-01-18 EP disclosed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP disclosed
CN-102834420-B Internal and external donor compounds for olefin polymerization catalysts ii BASF CORP. (US) 2014-10-22 CN disclosed
CN-104053682-A High activity catalyst component for olefin polymerization and method of using the same BASF SE 2014-09-17 CN disclosed
CN-102656194-A Mixed donor system for high melt flow and high activity BASF CORP 2012-09-05 CN disclosed
US-8227370-B2 High activity catalyst component for olefin polymerization and method of using the same BASF CORPORATION (US) 2012-07-24 US disclosed
CN-102574954-A Internal donor for olefin polymerization catalysts BASF CATALYSTS LLC 2012-07-11 CN disclosed
US-20120116031-A1 High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same BASF CORPORATION (US) 2012-05-10 US disclosed