Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.42 |
| ▸ | GAK | O14976 | 5/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.41 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26656452 | 0.83 | CA1 (0.44) | KDREGFR | |
| SCHEMBL26863392 | 0.81 | CCNA2 (0.39) | ALKERBB2 | |
| SCHEMBL26862940 | 0.81 | HTT (0.49) | HTTALKGAKRIPK2COQ8A | |
| SCHEMBL26863552 | 0.76 | GAK (0.35) | HTTGAKRIPK2EGFRGAA | |
| SCHEMBL26869039 | 0.76 | HTT (0.39) | HTTGAKRIPK2COQ8ANLK | |
| SCHEMBL26656471 | 0.74 | CNR1 (0.43) | HTTKMT2ATDP1 | |
| SCHEMBL26656472 | 0.74 | CNR1 (0.43) | HTTKMT2ATDP1 | |
| SCHEMBL30666114 | 0.74 | HSP90AA1 (0.38) | HTTKDRMAPTKMT2ATDP1 | |
| SCHEMBL26656462 | 0.74 | HSP90AA1 (0.38) | HTTKDRMAPTKMT2ATDP1 | |
| SCHEMBL25465044 | 0.70 | GAK (0.60) | HTTALKGAKRIPK2COQ8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023225001-A1 | NAPHTHYRIDINE BASED ENPP1 MODULATORS AND USES THEREOF | Vir Biotechnology, Inc. (US) | 2023-11-23 | — | — | WO | disclosed |