Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 6/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.32 |
| ▸ | CDK2 | P24941 | 5/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26869091 | 0.80 | KDM4E (0.35) | CHEK1CCNA2CDK2CCNA1KDM4E | |
| SCHEMBL26867729 | 0.80 | CDK2 (0.44) | CHEK1CCNA2CDK2CCNA1KDM4E | |
| SCHEMBL26869093 | 0.79 | CHEK1 (0.52) | CHEK1CCNA2CDK2CCNA1KDM4E | |
| SCHEMBL26868391 | 0.78 | CHEK1 (0.35) | CHEK1CCNA2CDK2CCNA1MAPT | |
| SCHEMBL26867958 | 0.78 | TYK2 (0.48) | — | |
| SCHEMBL26867726 | 0.71 | CCNA2 (0.48) | CHEK1CCNA2CDK2CCNA1CYP1A2 | |
| SCHEMBL26868115 | 0.68 | KDM4E (0.35) | CHEK1CCNA2CDK2CCNA1KDM4E | |
| SCHEMBL26868112 | 0.68 | KDM4E (0.35) | CHEK1CCNA2CDK2CCNA1KDM4E | |
| SCHEMBL26868158 | 0.68 | KDM4E (0.35) | CHEK1CCNA2CDK2CCNA1KDM4E | |
| SCHEMBL26874424 | 0.67 | KDM4E (0.36) | CHEK1CCNA2CDK2CCNA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282868-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE DERIVATIVE, AND COMPOSITIONS AND MEDICAL USE THEREOF | Shanghai Haiyan Pharmaceutical Technology Co., Ltd (CN) | 2023-11-29 | — | — | EP | disclosed |