Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 17/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 7/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 6/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 6/20 | 0.35 |
| ▸ | CDK9 | P50750 | 5/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.33 |
| ▸ | CDK7 | P50613 | 2/20 | 0.33 |
| ▸ | CCNH | P51946 | 2/20 | 0.33 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26868395 | 0.83 | PIM1 (0.36) | CDK2CHEK1CCNA2CCNA1PIM1 | |
| SCHEMBL26868450 | 0.81 | CDK2 (0.35) | CDK2GSK3BCHEK1CCNA2CCNA1 | |
| SCHEMBL26868396 | 0.80 | PIM1 (0.38) | CDK2CHEK1CCNA2CCNA1PIM1 | |
| SCHEMBL26868447 | 0.80 | CHEK1 (0.51) | CDK2CHEK1CCNA2CCNA1PIM1 | |
| SCHEMBL26873342 | 0.77 | CDK2 (0.36) | CDK2GSK3BCHEK1CCNA2CCNA1 | |
| SCHEMBL23181411 | 0.73 | RAB9A (0.54) | CDK2CHEK1CCNA2CCNA1CDK9 | |
| SCHEMBL26868026 | 0.73 | CDK2 (0.37) | CDK2GSK3BCHEK1CCNA2CCNA1 | |
| SCHEMBL26868111 | 0.72 | PIM1 (0.36) | CDK2CHEK1CCNA2CCNA1PIM1 | |
| SCHEMBL23181597 | 0.72 | KDM4E (0.40) | CDK2GSK3BCHEK1CCNA2CCNA1 | |
| SCHEMBL26868594 | 0.72 | CDK2 (0.38) | CDK2GSK3BCHEK1CCNA2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282868-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE DERIVATIVE, AND COMPOSITIONS AND MEDICAL USE THEREOF | Shanghai Haiyan Pharmaceutical Technology Co., Ltd (CN) | 2023-11-29 | — | — | EP | disclosed |