Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 7/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.39 |
| ▸ | CDK9 | P50750 | 6/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.36 |
| ▸ | CDK1 | P06493 | 4/20 | 0.36 |
| ▸ | CDK7 | P50613 | 4/20 | 0.35 |
| ▸ | GSK3B | P49841 | 4/20 | 0.35 |
| ▸ | CDK12 | Q9NYV4 | 3/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.35 |
| ▸ | GSK3A | P49840 | 2/20 | 0.35 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.35 |
| ▸ | CCNK | O75909 | 2/20 | 0.35 |
| ▸ | CCNH | P51946 | 2/20 | 0.35 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.35 |
| ▸ | CDK13 | Q14004 | 2/20 | 0.35 |
| ▸ | CCNT2 | O60583 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26875677 | 0.85 | MEN1 (0.36) | CDK2CHEK1CDK9CDK5CDK1 | |
| SCHEMBL26869020 | 0.82 | CDK2 (0.54) | CDK2CCNA2CCNA1CHEK1CDK9 | |
| SCHEMBL26868955 | 0.80 | CHEK1 (0.54) | CDK2CCNA2CCNA1CHEK1CDK9 | |
| SCHEMBL26869324 | 0.80 | TYK2 (0.36) | CDK2CHEK1CDK9CDK5CDK1 | |
| SCHEMBL26868024 | 0.77 | CHEK1 (0.53) | CDK2CCNA2CCNA1CHEK1GSK3B | |
| SCHEMBL26874963 | 0.77 | CDK2 (0.42) | CDK2CDK9CDK5CDK1CDK7 | |
| SCHEMBL26869077 | 0.74 | CDK9 (0.38) | CDK2CCNA2CCNA1CHEK1CDK9 | |
| SCHEMBL27383991 | 0.72 | TYK2 (0.46) | CDK2CCNA2CCNA1CHEK1CDK9 | |
| SCHEMBL26873489 | 0.69 | CSNK2B (0.44) | CDK2CHEK1CDK9CDK7CDK12 | |
| SCHEMBL26869434 | 0.68 | CDK9 (0.47) | CDK2CCNA2CCNA1CDK9CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282868-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE DERIVATIVE, AND COMPOSITIONS AND MEDICAL USE THEREOF | Shanghai Haiyan Pharmaceutical Technology Co., Ltd (CN) | 2023-11-29 | — | — | EP | disclosed |