Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 18/20 | 0.37 |
| ▸ | CDK2 | P24941 | 17/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 16/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 16/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26869090 | 0.97 | CHEK1 (0.37) | CHEK1CDK2CCNA2CCNA1GSK3B | |
| SCHEMBL26868107 | 0.95 | CHEK1 (0.36) | CHEK1CDK2CCNA2CCNA1 | |
| SCHEMBL26868951 | 0.83 | CHEK1 (0.37) | CHEK1CDK2CCNA2CCNA1 | |
| SCHEMBL26868955 | 0.81 | CHEK1 (0.54) | CHEK1CDK2CCNA2CCNA1 | |
| SCHEMBL26869018 | 0.80 | CHEK1 (0.37) | CHEK1CDK2CCNA2CCNA1 | |
| SCHEMBL26868957 | 0.80 | CDK2 (0.38) | CHEK1CDK2CCNA2CCNA1GSK3B | |
| SCHEMBL26868953 | 0.80 | CHEK1 (0.33) | CHEK1CDK2CCNA2CCNA1 | |
| SCHEMBL26869020 | 0.78 | CDK2 (0.54) | CHEK1CDK2CCNA2CCNA1GSK3B | |
| SCHEMBL14394867 | 0.77 | CHEK1 (0.39) | CHEK1CDK2CCNA2CCNA1 | |
| SCHEMBL26869019 | 0.77 | CHEK1 (0.33) | CHEK1CDK2CCNA2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282868-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE DERIVATIVE, AND COMPOSITIONS AND MEDICAL USE THEREOF | Shanghai Haiyan Pharmaceutical Technology Co., Ltd (CN) | 2023-11-29 | — | — | EP | disclosed |