SCHEMBL2686980

SCHEMBL2686980

FC1CCCCCC1.FCC1CCCCCC1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CHRM5 P08912 2/20 0.33
CYP1A2 P05177 1/20 0.33
ADRA2C P18825 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM1 P11229 1/20 0.33
SIGMAR1 Q99720 1/20 0.31
ADH1B P00325 1/20 0.31
ADH1C P00326 1/20 0.31
ADH1A P07327 1/20 0.31
ADH4 P08319 1/20 0.31
ADH7 P40394 1/20 0.31
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL604339 0.88
SCHEMBL21467045 0.88 CHRM5 (0.39) CHRM5CYP1A2ADRA2CCHRM2CHRM4
SCHEMBL169425 0.88
SCHEMBL497934 0.85
SCHEMBL14193884 0.79
SCHEMBL602116 0.78
SCHEMBL2283214 0.78 ALDH1A1 (0.36)
SCHEMBL10282692 0.78 ALDH1A1 (0.36)
SCHEMBL22790683 0.78 ALDH1A1 (0.36)
SCHEMBL19219867 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7081092-B2 Methods and apparatus for monitoring and quantifying the movement of fluid IMCOR PHARMACEUTICAL COMPANY (US) 2006-07-25 US claimed
US-20050049484-A1 Methods and apparatus for monitoring and quantifying the movement of fluid TARGESON, INC. 2005-03-03 US claimed
US-6802813-B2 Methods and apparatus for monitoring and quantifying the movement of fluid IMCOR PHARMACEUTICAL CO. 2004-10-12 US claimed
US-20030220563-A1 Methods and apparatus for monitoring and quantifying the movement of fluid TARGESON, INC. 2003-11-27 US claimed
US-20020065467-A1 Methods and apparatus for monitoring and quantifying the movement of fluid SCHUTT ERNEST G (US) 2002-05-30 US claimed
WO-1998053855-A1 METHODS AND APPARATUS FOR MONITORING AND QUANTIFYING THE MOVEMENT OF FLUID ALLIANCE PHARMACEUTICAL CORP. (US) 1998-12-03 WO claimed
US-9554993-B2 Pulmonary delivery particles comprising an active agent NOVARTIS AG (CH) 2017-01-31 US disclosed
US-8168223-B1 Engineered particles and methods of use NOVARTIS PHARMA AG (CH) 2012-05-01 US disclosed
US-20100272823-A1 PULMONARY DELIVERY PARTICLES COMPRISING WATER INSOLUBLE OR CRYSTALLINE ACTIVE AGENTS NOVARTIS PHARMA AG (CH) 2010-10-28 US disclosed
EP-1019022-B2 METHOD FOR FORMING A POWDER COMPRISING PERFORATED MICROPARTICLES NOVARTIS AG (CH) 2010-07-28 EP disclosed
US-20080233194-A1 Dispersion for pulmonary delivery of a bioactive agent NEKTAR THERAPEUTICS (US) 2008-09-25 US disclosed
US-7393544-B2 Dispersion for pulmonary delivery of a bioactive agent NEKTAR THERAPEUTICS (US) 2008-07-01 US disclosed
US-7306787-B2 Engineered particles and methods of use NEKTAR THERAPEUTICS (US) 2007-12-11 US disclosed
US-20020188281-A1 Stabilized bioactive preparations and method of use NOVARTIS PHARMA AG (CH) 2002-12-12 US disclosed
US-6433040-B1 ADMINISTERING NONAQUEOUS SUSPENSION IN LIQUID FLUOROCHEMICAL WITH PLURALITY OF PERFORATED MICROSTRUCTURES FILLED WITH BIOACTIVE AGENT DISPERSED THERIN TO NOSE OR LUNGS; DRUG DELIVERY INHALE THERAPEUTIC SYSTEMS, INC. 2002-08-13 US disclosed
US-20020065467-A1 Methods and apparatus for monitoring and quantifying the movement of fluid SCHUTT ERNEST G (US) 2002-05-30 US disclosed
EP-1019020-A1 STABILIZED BIOACTIVE PREPARATIONS AND METHODS OF USE Inhale Therapeutic Systems, Inc. (US) 2000-07-19 EP disclosed
WO-1999016420-A9 STABILIZED PREPARATIONS FOR USE IN NEBULIZERS ALLIANCE PHARMA (US) 1999-06-17 WO disclosed
WO-1999016421-A1 STABILIZED BIOACTIVE PREPARATIONS AND METHODS OF USE INHALE THERAPEUTIC SYSTEMS, INC. (US) 1999-04-08 WO disclosed
WO-1998053855-A1 METHODS AND APPARATUS FOR MONITORING AND QUANTIFYING THE MOVEMENT OF FLUID ALLIANCE PHARMACEUTICAL CORP. (US) 1998-12-03 WO disclosed