Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26871074 | 0.95 | KDM4E (0.35) | KDM4EALDH1A1MAPTRAB9AHTT | |
| SCHEMBL26871082 | 0.82 | CDK2 (0.36) | KDM4EALDH1A1MAPTRAB9AMEN1 | |
| SCHEMBL26871088 | 0.80 | KDM4E (0.32) | KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL26868395 | 0.78 | PIM1 (0.36) | KDM4EALDH1A1MAPTRAB9AHTT | |
| SCHEMBL26872817 | 0.76 | RAB9A (0.46) | KDM4EALDH1A1MAPTRAB9ACSNK2A1 | |
| SCHEMBL26873342 | 0.75 | CDK2 (0.36) | KDM4EALDH1A1MAPTRAB9AMEN1 | |
| SCHEMBL26871132 | 0.75 | PDE10A (0.49) | — | |
| SCHEMBL26870979 | 0.74 | KDM4E (0.36) | KDM4EALDH1A1MAPTRAB9AMEN1 | |
| SCHEMBL26873337 | 0.73 | CDK2 (0.39) | KDM4EMAPTRAB9A | |
| SCHEMBL26871180 | 0.72 | KCNH2 (0.36) | KDM4EALDH1A1MAPTRAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282868-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE DERIVATIVE, AND COMPOSITIONS AND MEDICAL USE THEREOF | Shanghai Haiyan Pharmaceutical Technology Co., Ltd (CN) | 2023-11-29 | — | — | EP | disclosed |