SCHEMBL2687261

SCHEMBL2687261

CCCOCC1(C(=O)CCC)c2ccccc2-c2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.37
PDK2 Q15119 3/20 0.36
ALDH1A1 P00352 2/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
MTTP P55157 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2685785 0.92 MTTP (0.38) APEX1PDK2MTTP
SCHEMBL2688172 0.92 PDK2 (0.40) PDK2ALDH1A1MTTP
SCHEMBL2686863 0.90 SOAT1 (0.39) PDK2MTTP
SCHEMBL2687380 0.90 PDK2 (0.41) PDK2ALDH1A1MTTPLMNA
SCHEMBL2687643 0.90 PDK2 (0.37) APEX1PDK2ALDH1A1MTTPLMNA
SCHEMBL2686958 0.90 APEX1 (0.38) APEX1PDK2ALDH1A1NPC1RAB9A
SCHEMBL2687565 0.89 SOAT1 (0.41) PDK2ALDH1A1LMNA
SCHEMBL2689008 0.89 SOAT1 (0.41) PDK2ALDH1A1LMNA
SCHEMBL2688054 0.89 SOAT1 (0.41) PDK2ALDH1A1LMNA
SCHEMBL2686305 0.88 PDK2 (0.38) APEX1PDK2ALDH1A1MTTPLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3118226-A1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF Corporation (US) 2017-01-18 EP claimed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP claimed
EP-2782938-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF Corporation (US) 2014-10-01 EP claimed
WO-2013077837-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF CORPORATION (US) 2013-05-30 WO claimed
US-8227370-B2 High activity catalyst component for olefin polymerization and method of using the same BASF CORPORATION (US) 2012-07-24 US claimed
US-20120116031-A1 High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same BASF CORPORATION (US) 2012-05-10 US claimed
CN-107207657-B Process for preparing spherical polymerization catalyst components for olefin polymerization 格雷斯公司 2020-03-03 CN disclosed
EP-3118226-A1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF Corporation (US) 2017-01-18 EP disclosed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP disclosed
EP-2782938-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF Corporation (US) 2014-10-01 EP disclosed
WO-2013077837-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF CORPORATION (US) 2013-05-30 WO disclosed
US-8227370-B2 High activity catalyst component for olefin polymerization and method of using the same BASF CORPORATION (US) 2012-07-24 US disclosed
US-20120116031-A1 High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same BASF CORPORATION (US) 2012-05-10 US disclosed