Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.61 |
| ▸ | CA2 | P00918 | 5/20 | 0.61 |
| ▸ | EGFR | P00533 | 3/20 | 0.56 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.56 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2688266 | 0.93 | MEN1 (0.56) | CA1CA2EGFRERBB2ERBB3 | |
| SCHEMBL2686716 | 0.91 | MEN1 (0.56) | EGFRERBB2ERBB3KDRPTK2 | |
| SCHEMBL2688532 | 0.91 | CA1 (0.66) | CA1CA2EGFRERBB2ERBB3 | |
| SCHEMBL8171059 | 0.84 | CA1 (0.73) | CA1CA2EGFRERBB2ERBB3 | |
| SCHEMBL11208392 | 0.84 | EGFR (0.74) | CA1CA2EGFRERBB2ERBB3 | |
| SCHEMBL2686830 | 0.84 | EGFR (0.65) | CA1CA2EGFRERBB2ERBB3 | |
| SCHEMBL2687368 | 0.84 | EGFR (0.50) | EGFRERBB2ERBB3KDRPTK2 | |
| SCHEMBL2686834 | 0.84 | MEN1 (0.49) | EGFRERBB2ERBB3KDRPTK2 | |
| SCHEMBL2688704 | 0.83 | EGFR (0.62) | EGFRERBB2ERBB3KDRPTK2 | |
| SCHEMBL2687298 | 0.81 | MEN1 (0.59) | CA1CA2EGFRERBB2ERBB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168796-B2 | Fluorescent agent having ethynyl group | NIPPON CHEMICAL WORKS CO., LTD. (JP) | 2012-05-01 | — | — | US | disclosed |
| US-20100298573-A1 | FLUORESCENT AGENT HAVING ETHYNYL GROUP | NIPPON CHEMICAL WORKS CO., LTD (JP) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298573-A1 | FLUORESCENT AGENT HAVING ETHYNYL GROUP | IK, CCNE1, TAS2R45 | CA1 3936/4885CA2 3181/4885EGFR 427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.