SCHEMBL268739

SCHEMBL268739

OCCCOCCCOCCCO

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.53
MAPK1 P28482 1/20 0.53
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
THRB P10828 1/20 0.43
HTT P42858 1/20 0.43
MAPT P10636 1/20 0.43
GAA P10253 1/20 0.39
ALDH1A1 P00352 3/20 0.35
CYP4F2 P78329 1/20 0.34
CYP4A11 Q02928 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.32
LMNA P02545 2/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31665952 1.00 TSHR (0.53) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL29862215 1.00 TSHR (0.53) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL5426255 1.00 TSHR (0.53) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL31665954 1.00 TSHR (0.53) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL17932914 1.00 TSHR (0.53) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL23528602 1.00 TSHR (0.53) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL5671453 1.00 TSHR (0.53) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL269039 1.00 TSHR (0.53) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL18364678 1.00 TSHR (0.53) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL29939047 1.00 TSHR (0.53) TSHRMAPK1MEN1KMT2ATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 308 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4382588-A1 ADDITIVES FOR IMPROVING THERMAL STABILITY OF FUELS BASF SE (DE) 2024-06-12 EP claimed
WO-2024002748-A1 METHOD FOR MANUFACTURE OF ETHYLENEAMINES BASF SE (DE) 2024-01-04 WO claimed
CN-114316197-B Thermoplastic polyurethane adhesive with low polarity and high heat resistance and application thereof 万华化学集团股份有限公司 2023-07-14 CN claimed
CN-114316197-A Low-polarity high-heat-resistance thermoplastic polyurethane adhesive and application thereof 万华化学集团股份有限公司 2022-04-12 CN claimed
EP-3886904-B1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-04-22 EP disclosed
EP-3530703-B1 POLYETHER-MODIFIED SILICONE COMPOSITION, SURFACTANT, FOAM STABILIZER, POLYURETHANE FOAM FORMING COMPOSITION, AND COSMETIC PREPARATION INCLUDING SAID COMPOSITION, AND METHOD FOR PRODUCING SAID COMPOSITION DOW TORAY CO LTD (JP) 2026-03-11 EP disclosed
US-20250163042-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2025-05-22 US disclosed
US-20250136625-A1 PROCESS FOR THE PREPARATION OF ORGANIC SILICON COMPOUNDS BASF SE (DE) 2025-05-01 US disclosed
US-12258341-B2 IRAK degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2025-03-25 US disclosed
EP-4476232-A1 PROCESS FOR THE PREPARATION OF ORGANIC SILICON COMPOUNDS BASF SE (DE) 2024-12-18 EP disclosed
US-20240409489-A1 METHOD FOR PRODUCING FLUORINATED POLYETHER RESONAC CORPORATION (JP) 2024-12-12 US disclosed
WO-2024214529-A1 MAGNETIC RECORDING MEDIUM LUBRICANT 株式会社レゾナック 2024-10-17 WO disclosed
US-20020086238-A1 Capable of forming a planographic plate having excellent plate life; capable of directly being engraved from digital data of a computer or like by recording with solid state laser and a semiconductor laser irradiating infrared rays FUJIFILM CORPORATION (JP) 2002-07-04 US disclosed
EP-1213619-A1 Method for preparing lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2002-06-12 EP disclosed
EP-1195646-A1 Photosensitive lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2002-04-10 EP disclosed
US-20010026902-A1 A support member, a light-to-heat conversion layer that contains a polyurethane with carboxyl group, and a silicone rubber layer; does not generate toxic gas at the time of image formation and printing plate preparation FUJIFILM CORPORATION (JP) 2001-10-04 US disclosed
EP-1136255-A2 Image recording material FUJI PHOTO FILM CO., LTD. (JP) 2001-09-26 EP disclosed
EP-1112843-A2 Waterless planographic printing plate precursor and production method thereof FUJI PHOTO FILM CO., LTD. (JP) 2001-07-04 EP disclosed
EP-1096314-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-05-02 EP disclosed
EP-0949540-A1 Method for producing lithographic printing plate suitable for laser scan exposure, and photopolymerizable composition FUJI PHOTO FILM CO., LTD (JP) 1999-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240409489-A1 METHOD FOR PRODUCING FLUORINATED POLYETHER MRPL21, RPS4X, MLX TSHR 1462/4885MAPK1 2927/4885MEN1 721/4885
US-12258341-B2 IRAK degraders and uses thereof IRAK2, IRAK3, IRAK1 TSHR 3319/4885MAPK1 2017/4885MEN1 4055/4885
US-20250163042-A1 IRAK DEGRADERS AND USES THEREOF IRAK2, IRAK3, IRAK1 TSHR 3319/4885MAPK1 2017/4885MEN1 4055/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.