Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 5/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.36 |
| ▸ | CDK9 | P50750 | 5/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | CLK2 | P49760 | 2/20 | 0.35 |
| ▸ | CLK3 | P49761 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | MAP3K8 | P41279 | 2/20 | 0.35 |
| ▸ | IKBKB | O14920 | 2/20 | 0.35 |
| ▸ | CHUK | O15111 | 2/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29691622 | 0.99 | ENPP1 (0.41) | BTKENPP1CCNT1CDK9NUDT1 | |
| Hydrochloric Acid SCHEMBL26679799 | 0.99 | ENPP1 (0.41) | BTKENPP1CCNT1CDK9NUDT1 | |
| SCHEMBL29248823 | 0.89 | BTK (0.42) | BTKENPP1CCNT1CDK9PDE3B | |
| Hydrochloric Acid SCHEMBL29691577 | 0.88 | ENPP1 (0.42) | BTKENPP1CCNT1CDK9PDE3B | |
| Hydrochloric Acid SCHEMBL26679856 | 0.88 | ENPP1 (0.42) | BTKENPP1CCNT1CDK9PDE3B | |
| SCHEMBL26679912 | 0.84 | BTK (0.39) | BTKENPP1CCNT1CDK9PDE3B | |
| SCHEMBL24600499 | 0.84 | BTK (0.40) | BTKENPP1CCNT1CDK9NUDT1 | |
| Hydrochloric Acid SCHEMBL29691615 | 0.83 | BTK (0.39) | BTKENPP1CCNT1CDK9NUDT1 | |
| Hydrochloric Acid SCHEMBL26679831 | 0.83 | BTK (0.39) | BTKENPP1CCNT1CDK9NUDT1 | |
| SCHEMBL29248818 | 0.83 | BTK (0.45) | BTKENPP1CCNT1CDK9NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116669726-A | Novel naphthyridinone derivatives having inhibitory activity against exonuclease-phosphodiesterase and use thereof | 谛希诺生物科技有限公司 | 2023-08-29 | — | — | CN | disclosed |