Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 8/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 6/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 3/20 | 0.34 |
| ▸ | CHUK | O15111 | 3/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL26679901 | 0.90 | CDK9 (0.37) | CDK9CCNT1PDE3BPDE3AIKBKB | |
| SCHEMBL29248823 | 0.86 | BTK (0.42) | BTKENPP1CDK9CCNT1PDE3B | |
| Hydrochloric Acid SCHEMBL29691577 | 0.85 | ENPP1 (0.42) | BTKENPP1CDK9CCNT1PDE3B | |
| Hydrochloric Acid SCHEMBL26679856 | 0.85 | ENPP1 (0.42) | BTKENPP1CDK9CCNT1PDE3B | |
| SCHEMBL26877271 | 0.84 | BTK (0.41) | BTKENPP1CDK9CCNT1PDE3B | |
| SCHEMBL24600499 | 0.84 | BTK (0.40) | BTKENPP1CDK9CCNT1PDE3B | |
| Hydrochloric Acid SCHEMBL26679799 | 0.83 | ENPP1 (0.41) | BTKENPP1CDK9CCNT1PDE3B | |
| Hydrochloric Acid SCHEMBL29691622 | 0.83 | ENPP1 (0.41) | BTKENPP1CDK9CCNT1PDE3B | |
| Hydrochloric Acid SCHEMBL29691615 | 0.83 | BTK (0.39) | BTKENPP1CDK9CCNT1PDE3B | |
| Hydrochloric Acid SCHEMBL26679831 | 0.83 | BTK (0.39) | BTKENPP1CDK9CCNT1PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240140944-A1 | NOVEL NAPHTHYRIDINONE DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE AND USE THEREOF | TXINNO BIOSCIENCE INC. (KR) | 2024-05-02 | — | — | US | claimed |
| EP-4276100-A1 | NOVEL NAPHTHYRIDINONE DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE AND USE THEREOF | Txinno Bioscience Inc. (KR) | 2023-11-15 | — | — | EP | claimed |
| CN-116669726-A | Novel naphthyridinone derivatives having inhibitory activity against exonuclease-phosphodiesterase and use thereof | 谛希诺生物科技有限公司 | 2023-08-29 | — | — | CN | claimed |
| US-20240140944-A1 | NOVEL NAPHTHYRIDINONE DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE AND USE THEREOF | TXINNO BIOSCIENCE INC. (KR) | 2024-05-02 | — | — | US | disclosed |
| EP-4276100-A1 | NOVEL NAPHTHYRIDINONE DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE AND USE THEREOF | Txinno Bioscience Inc. (KR) | 2023-11-15 | — | — | EP | disclosed |
| CN-116669726-A | Novel naphthyridinone derivatives having inhibitory activity against exonuclease-phosphodiesterase and use thereof | 谛希诺生物科技有限公司 | 2023-08-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240140944-A1 | NOVEL NAPHTHYRIDINONE DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE AND USE THEREOF | ENPP1, ENPP3, ENTPD5 | BTK 3874/4885ENPP1 1/4885CDK9 1169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.