Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 7/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.53 |
| ▸ | AURKA | O14965 | 4/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | BCR | P11274 | 2/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
| ▸ | AURKC | Q9UQB9 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | PRKACG | P22612 | 1/20 | 0.43 |
| ▸ | PRKACB | P22694 | 1/20 | 0.43 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL26679853 | 0.99 | PTK6 (0.52) | PTK6ERBB2AURKAAURKBSRC | |
| Hydrochloric Acid SCHEMBL29691563 | 0.99 | PTK6 (0.52) | PTK6ERBB2AURKAAURKBSRC | |
| SCHEMBL24600560 | 0.83 | AURKA (0.59) | PTK6ERBB2AURKAAURKBKDM4E | |
| Hydrochloric Acid SCHEMBL29691550 | 0.83 | TNNI3K (0.45) | PTK6ERBB2AURKAAURKBSRC | |
| Hydrochloric Acid SCHEMBL26679909 | 0.83 | TNNI3K (0.45) | PTK6ERBB2AURKAAURKBSRC | |
| Hydrochloric Acid SCHEMBL26679818 | 0.82 | AURKA (0.58) | PTK6ERBB2AURKAAURKBKDM4E | |
| Hydrochloric Acid SCHEMBL29691644 | 0.82 | AURKA (0.58) | PTK6ERBB2AURKAAURKBKDM4E | |
| Hydrochloric Acid SCHEMBL26679902 | 0.81 | PTK6 (0.41) | PTK6ERBB2AURKASRCEGFR | |
| SCHEMBL24600528 | 0.79 | PTK6 (0.40) | PTK6ERBB2AURKAAURKBSRC | |
| SCHEMBL24600527 | 0.78 | TNNI3K (0.41) | PTK6ERBB2AURKASRCEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116669726-A | Novel naphthyridinone derivatives having inhibitory activity against exonuclease-phosphodiesterase and use thereof | 谛希诺生物科技有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-116669726-A | Novel naphthyridinone derivatives having inhibitory activity against exonuclease-phosphodiesterase and use thereof | 谛希诺生物科技有限公司 | 2023-08-29 | — | — | CN | disclosed |