Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.32 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17712267 | 1.00 | CYP3A4 (0.34) | CYP3A4CYP2C9TMPRSS2BTN3A1 | |
| SCHEMBL19504146 | 1.00 | CYP3A4 (0.34) | CYP3A4CYP2C9TMPRSS2BTN3A1 | |
| SCHEMBL22143082 | 1.00 | CYP3A4 (0.34) | CYP3A4CYP2C9TMPRSS2BTN3A1 | |
| SCHEMBL17712268 | 1.00 | CYP3A4 (0.34) | CYP3A4CYP2C9TMPRSS2BTN3A1 | |
| SCHEMBL17712270 | 1.00 | CYP3A4 (0.34) | CYP3A4CYP2C9TMPRSS2BTN3A1 | |
| SCHEMBL23034488 | 1.00 | CYP3A4 (0.34) | CYP3A4CYP2C9TMPRSS2BTN3A1 | |
| SCHEMBL25013580 | 0.95 | TMPRSS2 (0.32) | TMPRSS2 | |
| SCHEMBL25519234 | 0.94 | CYP3A4 (0.34) | CYP3A4CYP2C9TMPRSS2BTN3A1 | |
| SCHEMBL25013991 | 0.93 | TMPRSS2 (0.32) | TMPRSS2 | |
| SCHEMBL30269833 | 0.92 | TMPRSS2 (0.30) | TMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381761-A1 | CATALYSTS AND THEIR USES IN ONE-POT DIASTEREOSELECTIVE SYNTHESIS OF REMDESIVIR | ACADEMIA SINICA (TW) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230381761-A1 | CATALYSTS AND THEIR USES IN ONE-POT DIASTEREOSELECTIVE SYNTHESIS OF REMDESIVIR | MTAP, PNP, ALKBH1 | CYP3A4 127/4885CYP2C9 347/4885TMPRSS2 663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.