⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20932923 | 0.57 | — | — | |
| SCHEMBL22899740 | 0.57 | — | — | |
| SCHEMBL20933006 | 0.57 | — | — | |
| SCHEMBL22905636 | 0.57 | — | — | |
| SCHEMBL12733214 | 0.56 | — | — | |
| SCHEMBL25067008 | 0.56 | — | — | |
| SCHEMBL24977996 | 0.53 | KDM4E (0.34) | — | |
| SCHEMBL24977966 | 0.53 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL20933020 | 0.53 | ALDH1A1 (0.39) | — | |
| SCHEMBL22899727 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365541-A1 | INHIBITOR OF ENHANCER OF ZESTE HOMOLOGUE 2, AND USE THEREOF | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2023-11-16 | — | — | US | disclosed |
| US-20230365541-A1 | INHIBITOR OF ENHANCER OF ZESTE HOMOLOGUE 2, AND USE THEREOF | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2023-11-16 | — | — | US | disclosed |