⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23823121 | 0.67 | — | — | |
| SCHEMBL17755568 | 0.60 | KDM4E (0.33) | — | |
| SCHEMBL18876126 | 0.57 | KDM4E (0.31) | — | |
| SCHEMBL12157070 | 0.55 | ADORA2A (0.33) | — | |
| SCHEMBL14282452 | 0.53 | — | — | |
| SCHEMBL15339525 | 0.53 | PDPK1 (0.32) | — | |
| SCHEMBL24284147 | 0.53 | KDM4E (0.32) | — | |
| SCHEMBL8581086 | 0.52 | PI4KA (0.32) | — | |
| SCHEMBL8737066 | 0.52 | — | — | |
| SCHEMBL18876081 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365541-A1 | INHIBITOR OF ENHANCER OF ZESTE HOMOLOGUE 2, AND USE THEREOF | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2023-11-16 | — | — | US | disclosed |
| US-20230365541-A1 | INHIBITOR OF ENHANCER OF ZESTE HOMOLOGUE 2, AND USE THEREOF | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2023-11-16 | — | — | US | disclosed |