SCHEMBL26880965

SCHEMBL26880965

Cc1c2c(c3nc[nH]c3c1C(C)(C)C)OC(C)(C(C)(C)C)O2

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.31
▸ CSNK2A2 P19784 1/20 0.31
▸ RAB9A P51151 1/20 0.31
▸ CSNK2B P67870 1/20 0.31
▸ CSNK2A1 P68400 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ DYRK1A Q13627 1/20 0.31
▸ CSNK2A3 Q8NEV1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23823295 0.67 CSNK2A1 (0.37) MEN1CSNK2A2RAB9ACSNK2BCSNK2A1
SCHEMBL18405893 0.59 LMNA (0.38) MEN1KMT2A
SCHEMBL12618885 0.57 PDPK1 (0.44) MEN1CSNK2A2RAB9ACSNK2BCSNK2A1
SCHEMBL17281080 0.56 PDPK1 (0.40) MEN1CSNK2A2RAB9ACSNK2BCSNK2A1
SCHEMBL19104229 0.55 PARP1 (0.35) RAB9A
SCHEMBL17307154 0.55 DPP4 (0.40) MEN1CSNK2A1KMT2ADYRK1A
SCHEMBL6364767 0.55 LMNA (0.38) MEN1KMT2A
SCHEMBL16589274 0.55 CSNK2A1 (0.38) MEN1CSNK2A2RAB9ACSNK2BCSNK2A1
SCHEMBL24854117 0.54 LMNA (0.37) MEN1KMT2A
SCHEMBL824416 0.54 CSNK2A1 (0.55) MEN1CSNK2A2RAB9ACSNK2BCSNK2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230365541-A1 INHIBITOR OF ENHANCER OF ZESTE HOMOLOGUE 2, AND USE THEREOF XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) 2023-11-16 — — US disclosed
US-20230365541-A1 INHIBITOR OF ENHANCER OF ZESTE HOMOLOGUE 2, AND USE THEREOF XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) 2023-11-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230365541-A1 INHIBITOR OF ENHANCER OF ZESTE HOMOLOGUE 2, AND USE THEREOF EZH2, BMI1, EZH1 MEN1 791/4885CSNK2A2 360/4885RAB9A 2688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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