Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.44 |
| ▸ | NPC1 | O15118 | 9/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | GCK | P35557 | 1/20 | 0.42 |
| ▸ | CHKA | P35790 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.42 |
| ▸ | TP53 | P04637 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.40 |
| ▸ | RELA | Q04206 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26884193 | 0.91 | RAB9A (0.44) | RAB9ANPC1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL26884196 | 0.81 | NPC1 (0.58) | RAB9ANPC1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL26884191 | 0.79 | RAB9A (0.48) | RAB9ANPC1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL330155 | 0.75 | TSHR (0.46) | RAB9ANPC1GCKCHKASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL20764968 | 0.74 | TSHR (0.44) | RAB9ANPC1GCKCHKASMN1; SMN2 | |
| SCHEMBL12307415 | 0.73 | TSHR (0.43) | RAB9ANPC1KMT2AGCKCHKA | |
| SCHEMBL26884258 | 0.73 | RAB9A (0.45) | RAB9ANPC1KMT2AGCKSMN1; SMN2 | |
| SCHEMBL980111 | 0.73 | MAPT (0.52) | RAB9ANPC1KMT2ACHKASMN1; SMN2 | |
| SCHEMBL15012213 | 0.73 | CHKA (0.45) | RAB9ANPC1KMT2AGCKCHKA | |
| SCHEMBL24329828 | 0.69 | RAB9A (0.44) | RAB9ANPC1KMT2ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382903-A1 | SMALL MOLECULE MODULATORS OF GP130 SIGNALING PATHWAYS, TOPICAL FORMULATIONS AND METHOD OF USE THEREOF | CARTHRONIX INC (US) | 2023-11-30 | — | — | US | disclosed |
| US-20230382903-A1 | SMALL MOLECULE MODULATORS OF GP130 SIGNALING PATHWAYS, TOPICAL FORMULATIONS AND METHOD OF USE THEREOF | CARTHRONIX INC (US) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382903-A1 | SMALL MOLECULE MODULATORS OF GP130 SIGNALING PATHWAYS, TOPICAL FORMULATIONS AND METHOD OF USE THEREOF | STAT1, STAT3, STAT6 | RAB9A 3504/4885NPC1 2133/4885KMT2A 4379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.