Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ICMT | O60725 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26884444 | 1.00 | ADORA2A (0.38) | ADORA2AADORA1CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL18079829 | 0.92 | ADORA2A (0.42) | ADORA2AADORA1CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL16544656 | 0.91 | CYP1A2 (0.42) | CYP1A2CYP2D6ALDH1A1KDM4EHPGD | |
| SCHEMBL16544648 | 0.91 | CYP1A2 (0.42) | CYP1A2CYP2D6ALDH1A1KDM4EHPGD | |
| SCHEMBL16544644 | 0.89 | CYP1A2 (0.43) | CYP1A2CYP2D6ALDH1A1KDM4EHPGD | |
| SCHEMBL26884443 | 0.87 | PDK2 (0.38) | ADORA2AADORA1ALDH1A1TSHRICMT | |
| SCHEMBL26884425 | 0.87 | HTR7 (0.38) | CYP1A2CYP2D6ALDH1A1KDM4EHPGD | |
| SCHEMBL26884426 | 0.87 | PDK2 (0.38) | ADORA2AADORA1ALDH1A1TSHRICMT | |
| SCHEMBL26884440 | 0.87 | HTR7 (0.38) | CYP1A2CYP2D6ALDH1A1KDM4EHPGD | |
| SCHEMBL18079825 | 0.79 | ADORA2A (0.42) | ADORA2AADORA1CYP1A2CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230373941-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230373941-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | CYP2E1, GPX1, ERCC1 | ADORA2A 3318/4885ADORA1 3478/4885CYP1A2 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.