Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.57 |
| ▸ | ACE | P12821 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.45 |
| ▸ | IL1RN | P18510 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26173212 | 1.00 | PTPN1 (0.57) | PTPN1ACEPPARGTSHRKLKB1 | |
| SCHEMBL26173250 | 0.96 | PTPN1 (0.58) | PTPN1ACEPPARGKLKB1GPR34 | |
| SCHEMBL26888062 | 0.94 | PTPN1 (0.55) | PTPN1ACEPPARGKLKB1GPR34 | |
| SCHEMBL27277512 | 0.91 | MMP3 (0.53) | PTPN1PPARGTSHR | |
| SCHEMBL26167593 | 0.90 | PTPN1 (0.56) | PTPN1ACEIL1RNERAP2ERAP1 | |
| SCHEMBL26875855 | 0.88 | PTPN1 (0.53) | PTPN1PPARGKLKB1GPR34 | |
| SCHEMBL24899346 | 0.87 | MMP3 (0.56) | PTPN1ACEPPARGKLKB1MME | |
| SCHEMBL26889000 | 0.87 | PTPN1 (0.57) | PTPN1ACEPPARGKLKB1GPR34 | |
| SCHEMBL26892213 | 0.87 | MME (0.50) | PTPN1ACEPPARGKLKB1GPR34 | |
| SCHEMBL26172463 | 0.87 | MME (0.50) | PTPN1ACEPPARGKLKB1GPR34 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023225661-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-11-23 | — | — | WO | disclosed |