Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CCNK | O75909 | 1/20 | 0.39 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.39 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26889215 | 0.92 | HTT (0.45) | HTTSMN1; SMN2HSD17B10CCNKCDK12 | |
| SCHEMBL26889268 | 0.87 | SMN1; SMN2 (0.41) | HTTSMN1; SMN2HSD17B10CCNKCDK12 | |
| SCHEMBL26889291 | 0.82 | CCNK (0.50) | CCNKCDK12 | |
| SCHEMBL26889111 | 0.80 | CCNK (0.40) | CCNKCDK12UTS2R | |
| SCHEMBL26889243 | 0.80 | CCNK (0.57) | CCNKCDK12HRH4 | |
| SCHEMBL30716680 | 0.78 | KDM5A (0.42) | HTTSMN1; SMN2HSD17B10CCNKCDK12 | |
| SCHEMBL21428737 | 0.78 | KDM5A (0.42) | HTTSMN1; SMN2HSD17B10CCNKCDK12 | |
| SCHEMBL26889101 | 0.74 | AXL (0.40) | CCNKCDK12KDM4ECYP1A2CYP2C19 | |
| SCHEMBL26686442 | 0.74 | CCNK (0.39) | CCNKCDK12 | |
| SCHEMBL30571033 | 0.73 | AXL (0.44) | CCNKCDK12UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023218201-A1 | IKK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |