Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CCNK | O75909 | 7/20 | 0.34 |
| ▸ | CDK12 | Q9NYV4 | 7/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26686642 | 0.83 | AXL (0.41) | AXLPRKCINUDT1DAOCDC7 | |
| SCHEMBL3415919 | 0.81 | AXL (0.44) | AXLPRKCINUDT1DAOCDC7 | |
| SCHEMBL30571033 | 0.81 | AXL (0.44) | AXLPRKCINUDT1DAOCDC7 | |
| SCHEMBL26686124 | 0.79 | AXL (0.38) | AXLPRKCINUDT1DAOCDC7 | |
| SCHEMBL21429079 | 0.78 | NUDT1 (0.59) | AXLPRKCINUDT1DAOCDC7 | |
| SCHEMBL31420473 | 0.78 | NUDT1 (0.59) | AXLPRKCINUDT1DAOCDC7 | |
| SCHEMBL30716680 | 0.77 | KDM5A (0.42) | AXLPRKCINUDT1DAOCDC7 | |
| SCHEMBL21428737 | 0.77 | KDM5A (0.42) | AXLPRKCINUDT1DAOCDC7 | |
| SCHEMBL26889157 | 0.77 | AXL (0.41) | AXLPRKCINUDT1DAOCDC7 | |
| SCHEMBL26889243 | 0.76 | CCNK (0.57) | AXLPRKCINUDT1DAOCDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023218201-A1 | IKK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |