SCHEMBL2689003

SCHEMBL2689003

O=S(=O)(O)c1c[c][c]c2ccccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MPL P40238 9/20 0.38
TTR P02766 1/20 0.38
CTRC Q99895 2/20 0.35
TSHR P16473 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
CYP1A2 P05177 2/20 0.33
COMT P21964 1/20 0.33
NSD2 O96028 1/20 0.33
MMP14 P50281 1/20 0.33
CASP6 P55212 1/20 0.33
AURKA O14965 1/20 0.33
AURKB Q96GD4 1/20 0.33
SUMO2 P61956 1/20 0.33
SUMO1 P63165 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP2 Q9HC62 1/20 0.33
SENP1 Q9P0U3 1/20 0.33
CHAT P28329 1/20 0.33
SNCA P37840 1/20 0.33
CTRB1 P17538 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7764278 0.81 ELANE (0.35)
SCHEMBL1486014 0.76 TTR (0.44) MPLTTRCYP1A2COMTNSD2
SCHEMBL2689051 0.76 TTR (0.44) MPLTTRCYP1A2COMTNSD2
SCHEMBL1804225 0.72 TTR (0.43) MPLTTRCTRCTSHRSMN1; SMN2
SCHEMBL6631686 0.69 MPL (0.41) MPLTTRCTRCCYP1A2NSD2
SCHEMBL6632432 0.69 MPL (0.44) MPLTTRCTRCCYP1A2COMT
SCHEMBL6631191 0.69 CYP2D6 (0.37) MPLTTRCTRCTSHRSMN1; SMN2
SCHEMBL703189 0.68 TTR (0.61) MPLTTRCTRCTSHRSMN1; SMN2
SCHEMBL29409575 0.68 TTR (0.61) MPLTTRCTRCTSHRSMN1; SMN2
SCHEMBL6633977 0.68 TTR (0.43) MPLTTRCTRCTSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1975205-B1 TRISAZO COMPOUND, INK COMPOSITION, RECORDING METHOD AND COLORED MATTER NIPPON KAYAKU KK (JP) 2012-05-02 EP disclosed
US-8167991-B2 Trisazo compound, ink composition, recording method, and colored article NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-05-01 US disclosed
US-20090062545-A1 Trisazo Compound, Ink Composition, Recording Method, and Colored Article NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-03-05 US disclosed
EP-1975205-A1 TRISAZO COMPOUND, INK COMPOSITION, RECORDING METHOD AND COLORED MATTER Nipponkayaku Kabushikikaisha (JP) 2008-10-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090062545-A1 Trisazo Compound, Ink Composition, Recording Method, and Colored Article JAK1, TMT1A, CDK1 MPL 3301/4885TTR 357/4885CTRC 1259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.