Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 2/20 | 0.32 |
| ▸ | CHAT | P28329 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | IDE | P14735 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | MPL | P40238 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1807070 | 0.76 | TTR (0.50) | TTRAURKAAURKBCYP1A2COMT | |
| SCHEMBL2689003 | 0.76 | MPL (0.38) | TTRAURKAAURKBCYP1A2COMT | |
| SCHEMBL6635201 | 0.71 | TTR (0.44) | TTRAURKAAURKBCYP1A2COMT | |
| SCHEMBL8747432 | 0.71 | TTR (0.44) | TTRAURKAAURKBCYP1A2COMT | |
| SCHEMBL29363198 | 0.71 | TTR (0.75) | TTRAURKAAURKBCYP1A2COMT | |
| SCHEMBL30233642 | 0.71 | TTR (0.75) | TTRAURKAAURKBCYP1A2COMT | |
| SCHEMBL6242 | 0.71 | TTR (0.75) | TTRAURKAAURKBCYP1A2COMT | |
| SCHEMBL1804225 | 0.70 | TTR (0.43) | TTRAURKAAURKBCYP1A2COMT | |
| SCHEMBL8659138 | 0.70 | TTR (0.51) | TTRAURKAAURKBCYP1A2COMT | |
| SCHEMBL7482596 | 0.70 | TTR (0.43) | TTRAURKAAURKBCYP1A2COMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130131112-A1 | SALTS OF 3-(4-AMINO-1-OXO-1,3-DIHYDRO-ISOINDOL-2-YL)PIPERIDINE-2,6-DIONE AND DERIVATIVES THEREOF, OR POLYMORPHS OF SALTS, PROCESS FOR PREPARING SAME AND USE THEREOF | TIANJIN MICHELE SCI-TECH DEVELOPMENT CO., LTD (CN) | 2013-05-23 | — | — | US | disclosed |
| US-20110060010-A1 | SALTS OF 3-(4-AMINO-1-OXO-1,3-DIHYDRO-ISOINDOL-2-YL)PIPERIDINE-2,6-DIONE AND DERIVATIVES THEREOF, OR POLYMORPHS OF SALTS, PROCESS FOR PREPARING SAME AND USE THEREOF | TIANJIN HEMAY BIO-TECH CO., LTD (CN) | 2011-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131112-A1 | SALTS OF 3-(4-AMINO-1-OXO-1,3-DIHYDRO-ISOINDOL-2-YL)PIPERIDINE-2,6-DIONE AND DERIVATIVES THEREOF, OR POLYMORPHS OF SALTS, PROCESS FOR PREPARING SAME AND USE THEREOF | AQP1, IDO1, PGF | TTR 2877/4885AURKA 2463/4885AURKB 3430/4885 |
| US-20110060010-A1 | SALTS OF 3-(4-AMINO-1-OXO-1,3-DIHYDRO-ISOINDOL-2-YL)PIPERIDINE-2,6-DIONE AND DERIVATIVES THEREOF, OR POLYMORPHS OF SALTS, PROCESS FOR PREPARING SAME AND USE THEREOF | AQP1, IDO1, PGF | TTR 2877/4885AURKA 2463/4885AURKB 3430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.