Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 17/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | MAT2A | P31153 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31543179 | 0.98 | MAPK1 (0.46) | MAPK1PIM1GRM4MAT2A | |
| Hydrochloric Acid SCHEMBL26685877 | 0.98 | MAPK1 (0.46) | MAPK1PIM1GRM4MAT2A | |
| SCHEMBL31692036 | 0.98 | MAPK1 (0.48) | MAPK1PIM1GRM4MAT2A | |
| SCHEMBL31543142 | 0.97 | MAPK1 (0.47) | MAPK1PIM1GRM4 | |
| SCHEMBL31543410 | 0.87 | MAPK1 (0.50) | MAPK1GRM4 | |
| SCHEMBL31543504 | 0.87 | MAPK1 (0.48) | MAPK1PIM1 | |
| Hydrochloric Acid SCHEMBL31543151 | 0.85 | MAPK1 (0.49) | MAPK1GRM4 | |
| SCHEMBL31144169 | 0.81 | PRKAB2 (0.46) | MAPK1 | |
| SCHEMBL26888296 | 0.81 | MAPK1 (0.45) | MAPK1 | |
| SCHEMBL31691866 | 0.81 | MAPK1 (0.46) | MAPK1GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250304577-A1 | TYK2 INHIBITORS | BIOGEN MA INC. | 2025-10-02 | — | — | US | disclosed |
| WO-2023220046-A1 | TYK2 INHIBITORS | BIOGEN MA INC. (US) | 2023-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250304577-A1 | TYK2 INHIBITORS | TYK2, JAK2, JAK1 | MAPK1 228/4885PIM1 248/4885GRM4 3812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.