⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionaldehyde SCHEMBL2457436 | 0.89 | — | — | |
| Propionaldehyde SCHEMBL11529495 | 0.88 | — | — | |
| Propionaldehyde SCHEMBL27762206 | 0.88 | ALDH1A1 (0.75) | — | |
| Propionaldehyde SCHEMBL19988098 | 0.87 | ALDH1A1 (0.53) | — | |
| Propionaldehyde SCHEMBL28988974 | 0.85 | — | — | |
| Propionaldehyde SCHEMBL10787498 | 0.85 | — | — | |
| Propionaldehyde SCHEMBL8391627 | 0.84 | — | — | |
| Propionaldehyde SCHEMBL28312820 | 0.84 | — | — | |
| Propionaldehyde SCHEMBL1332840 | 0.83 | — | — | |
| Propionaldehyde SCHEMBL4992 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104046600-A | Novel purpose of multi-arm polyethylene glycol (PEG) modification agent and use of multi-arm PEG modification agent in L-asparaginasum modification | ZONHON BIOPHARMA INST INC | 2014-09-17 | — | — | CN | claimed |
| CN-103403019-A | Engineered polypeptides having enhanced duration of action | AMYLIN PHARMACEUTICALS INC | 2013-11-20 | — | — | CN | claimed |
| CN-102234310-A | Polyethylene glycol modified protein separating and purifying method | Hangzhou jiuyuan gene engineering co ltd | 2011-11-09 | — | — | CN | claimed |
| CN-101352573-B | Recombinant human granulocyte colony stimulating factor lysine defect body modified by polyethyleneglycol | Hangzhou jiuyuan gene engineering co ltd | 2011-02-09 | — | — | CN | claimed |
| CN-101096664-A | Arginine deacylase covalent ornaments, its manufacturing method and application | BEIJING SL PHARMACEUTICAL TECH (CN) | 2008-01-02 | — | — | CN | claimed |
| US-12012452-B2 | Compositions monovalent for CD28 binding and methods of use | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-06-18 | — | — | US | disclosed |
| CN-113717735-B | Positive dielectric anisotropic liquid crystal compound, liquid crystal composition and liquid crystal display device | 烟台显华科技集团股份有限公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-114028610-B | Hydrophilic injection type skin filling composition and preparation method and application thereof | 北京诺康达医药科技股份有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-114099784-B | Injection type skin filling composition and preparation method and application thereof | 四川兴科蓉药业有限责任公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-114375333-A | Compositions comprising a propeptide of lysyl oxidase and uses thereof | 耶达研究及发展有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-114099784-A | Injection type skin filling composition and preparation method and application thereof | 四川兴科蓉药业有限责任公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-114028610-A | Hydrophilic injection type skin filling composition and preparation method and application thereof | 北京诺康达医药科技股份有限公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-1232500-A | Neuritin, a neurogene | AMGEN INC (US) | 1999-10-20 | — | — | CN | disclosed |
| CN-1219967-A | Glial cell line-derived neurotrophic factor receptor | AMGEN INC (US) | 1999-06-16 | — | — | CN | disclosed |
| EP-0909316-A1 | GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR RECEPTOR | AMGEN INC. (US) | 1999-04-21 | — | — | EP | disclosed |
| CN-1197461-A | Truncated glial cell line-derived neurotrophic factor | AMGEN INC (US) | 1998-10-28 | — | — | CN | disclosed |
| CN-1173183-A | Conjugates of BDNF and NT-3 with a water-soluble polymer | AMGEN INC (US) | 1998-02-11 | — | — | CN | disclosed |
| WO-1997040152-A1 | GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR RECEPTOR | AMGEN INC. (US) | 1997-10-30 | — | — | WO | disclosed |
| CN-1162978-A | Body weight regulators, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof | UNIV ROCKEFELLER (US) | 1997-10-22 | — | — | CN | disclosed |
| CN-1139932-A | N-terminally chemically modified protein compositions and methods | AMGEN INC (US) | 1997-01-08 | — | — | CN | disclosed |