Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.59 |
| ▸ | CNR2 | P34972 | 4/20 | 0.59 |
| ▸ | ESR1 | P03372 | 6/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | ESRRG | P62508 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4461728 | 0.92 | ESR1 (0.59) | CNR1CNR2ESR1ESR2ALDH1A1 | |
| SCHEMBL4467655 | 0.91 | ESR1 (0.60) | CNR1CNR2ESR1ESR2ALDH1A1 | |
| SCHEMBL29393508 | 0.90 | ESR1 (0.61) | CNR1CNR2ESR1ESR2ALDH1A1 | |
| SCHEMBL29479453 | 0.90 | ESR1 (0.61) | CNR1CNR2ESR1ESR2ALDH1A1 | |
| SCHEMBL37041 | 0.90 | ESR1 (0.61) | CNR1CNR2ESR1ESR2ALDH1A1 | |
| Water SCHEMBL11316268 | 0.88 | ESR1 (0.59) | CNR1CNR2ESR1ESR2ALDH1A1 | |
| SCHEMBL30713707 | 0.87 | ESR1 (0.61) | CNR1CNR2ESR1ESR2ALDH1A1 | |
| SCHEMBL10865833 | 0.87 | ESR1 (0.61) | CNR1CNR2ESR1ESR2ALDH1A1 | |
| SCHEMBL15961467 | 0.85 | ESR1 (0.52) | CNR1CNR2ESR1ESR2ALDH1A1 | |
| SCHEMBL2030501 | 0.85 | ESR2 (0.68) | CNR1CNR2ESR1ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102428061-B | Method for producing trisphenols and monoester substituted compounds thereof, and 4-acylaralkylphenol derivative | HONSHU CHEMICAL INDUSTRY Co.,Ltd. (JP) | 2015-09-30 | — | — | CN | claimed |
| US-9567281-B2 | 4-acylaralkylphenols and derivatives thereof | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-02-14 | — | — | US | disclosed |
| CN-104211588-B | 4-acylaralkylphenol derivative | 本州化学工业株式会社 | 2017-01-11 | — | — | CN | disclosed |
| CN-102428061-B | Method for producing trisphenols and monoester substituted compounds thereof, and 4-acylaralkylphenol derivative | HONSHU CHEMICAL INDUSTRY Co.,Ltd. (JP) | 2015-09-30 | — | — | CN | disclosed |
| US-9090547-B2 | Method for producing trisphenols and monoester-substituted products thereof, and 4-acylaralkylphenol derivatives | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2015-07-28 | — | — | US | disclosed |
| CN-104211588-A | 4-acylaralkylphenol derivative | HONSHU CHEMICAL IND | 2014-12-17 | — | — | CN | disclosed |
| US-20140221680-A1 | 4-Acylaralkylphenols and Derivatives Thereof | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-08-07 | — | — | US | disclosed |
| US-20120108853-A1 | METHOD FOR PRODUCING TRISPHENOLS AND MONOESTER-SUBSTITUTED PRODUCTS THEREOF, AND 4-ACYLARALKYLPHENOL DERIVATIVES | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-05-03 | — | — | US | disclosed |
| CN-102428061-A | Method for producing trisphenols and monoester substituted compounds thereof, and 4-acylaralkylphenol derivative | HONSHU CHEMICAL IND | 2012-04-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221680-A1 | 4-Acylaralkylphenols and Derivatives Thereof | UGT1A7, CYP19A1, UGT2B7 | CNR1 3721/4885CNR2 3236/4885ESR1 311/4885 |
| US-20120108853-A1 | METHOD FOR PRODUCING TRISPHENOLS AND MONOESTER-SUBSTITUTED PRODUCTS THEREOF, AND 4-ACYLARALKYLPHENOL DERIVATIVES | CYP19A1, MTTP, CYP4X1 | CNR1 4367/4885CNR2 4141/4885ESR1 588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.