SCHEMBL4467655

SCHEMBL4467655

CC(C)(c1cccc(C(C)(C)c2ccc(O)c(Cl)c2)c1)c1ccc(O)c(Cl)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.60
ESR2 Q92731 5/20 0.60
CNR1 P21554 4/20 0.49
CNR2 P34972 4/20 0.49
KLF10 Q13118 1/20 0.47
ALOX15 P16050 2/20 0.44
ALOX12 P18054 1/20 0.44
ALDH1A1 P00352 2/20 0.44
CYP3A4 P08684 2/20 0.44
HSD17B10 Q99714 3/20 0.43
TSHR P16473 2/20 0.43
RORC P51449 1/20 0.43
HPGD P15428 2/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
AR P10275 1/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
HTR6 P50406 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL37041 0.92 ESR1 (0.61) ESR1ESR2CNR1CNR2KLF10
SCHEMBL29479453 0.92 ESR1 (0.61) ESR1ESR2CNR1CNR2KLF10
SCHEMBL29393508 0.92 ESR1 (0.61) ESR1ESR2CNR1CNR2KLF10
SCHEMBL2689237 0.91 CNR1 (0.59) ESR1ESR2CNR1CNR2KLF10
SCHEMBL4461728 0.90 ESR1 (0.59) ESR1ESR2CNR1CNR2KLF10
Water SCHEMBL11316268 0.90 ESR1 (0.59) ESR1ESR2CNR1CNR2KLF10
SCHEMBL20761542 0.88 ESR1 (0.47) ESR1ESR2CNR1CNR2KLF10
SCHEMBL11430135 0.85 ESR1 (0.77) ESR1ESR2CNR1CNR2KLF10
SCHEMBL9716020 0.85 ESR1 (0.53) ESR1ESR2CNR1CNR2KLF10
SCHEMBL13571714 0.85 ESR1 (0.77) ESR1ESR2CNR1CNR2KLF10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582355-B2 Optical unit using plastic lenses FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-20060046065-A1 Optical unit using plastic lenses FUJI PHOTO FILM CO., LTD. 2006-03-02 US disclosed
US-6028161-A EXCELLENT TRANSPARENCY, HEAT RESISTANCE AND MECHANICAL PROPERTIES AND A LOW BIREFRINGENCE, MELT FLUIDITY AND MOLDABILITY; AN OPTICAL DISK, LENS AND AN OPTICAL FIBER MITSUI CHEMICALS, INC. (JP) 2000-02-22 US disclosed
EP-0926180-A2 A polycarbonate copolymer and applications thereof Mitsui Chemicals, Inc. (JP) 1999-06-30 EP disclosed