⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131124 | 0.76 | — | — | |
| SCHEMBL588224 | 0.73 | — | — | |
| SCHEMBL4074455 | 0.70 | — | — | |
| SCHEMBL1029972 | 0.70 | — | — | |
| SCHEMBL9723039 | 0.70 | — | — | |
| SCHEMBL23062 | 0.70 | — | — | |
| SCHEMBL3325067 | 0.70 | — | — | |
| SCHEMBL1678745 | 0.70 | — | — | |
| SCHEMBL2153288 | 0.67 | TSHR (1.00) | — | |
| SCHEMBL22537 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2394 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116655673-A | Boron-nitrogen coordination bond-containing spiro compound and organic electroluminescent device | 江汉大学 | 2023-08-29 | — | — | CN | claimed |
| CN-116655672-A | Boron-nitrogen compound and organic electroluminescent device | 江汉大学 | 2023-08-29 | — | — | CN | claimed |
| CN-112654620-B | Novel pyrazolopyridine compounds for the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2023-08-04 | — | — | CN | claimed |
| EP-3847173-B1 | NOVEL PYRAZOLOPYRIDINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | HOFFMANN LA ROCHE (CH) | 2023-04-12 | — | — | EP | claimed |
| US-20210355122-A1 | PYRAZOLOPYRIDINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | HOFFMANN-LA ROCHE INC. (US) | 2021-11-18 | — | — | US | claimed |
| EP-3847173-A1 | NOVEL PYRAZOLOPYRIDINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. Hoffmann-La Roche AG (CH) | 2021-07-14 | — | — | EP | claimed |
| CN-112654620-A | Novel pyrazolopyridine compounds for the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2021-04-13 | — | — | CN | claimed |
| CN-110724128-A | Small molecule luminescent material based on 1, 3-naphthyridine (quinazoline), preparation method and application thereof | 哈尔滨工业大学 | 2020-01-24 | — | — | CN | claimed |
| US-20190284200-A1 | MODULATORS OF THE BETA-3 ADRENERGIC RECEPTOR USEFUL FOR THE TREATMENT OR PREVENTION OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. | 2019-09-19 | — | — | US | claimed |
| US-9394297-B2 | Amides as pim inhibitors | AMGEN INC. (US) | 2016-07-19 | — | — | US | claimed |
| EP-0296592-B1 | AMINOPROPANOL DERIVATIVES OF 3-(2-HYDROXYPHENYL)-1-PROPANONE, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | Helopharm W. Petrik GmbH & Co.KG. (DE) | 1992-02-12 | — | — | EP | claimed |
| EP-0297435-B1 | AMINOPROPANOL DERIVATIVES OF 3-(3'-HYDROXYPHENYL)-1-PROPANONE, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | Helopharm W. Petrik GmbH & Co.KG. (DE) | 1991-10-16 | — | — | EP | claimed |
| WO-1991009834-A1 | o-HYDROXY-β-(1-NAPHTHYL)-PROPIOPHENONE DERIVATIVES, PROCESS FOR PRODUCING THEM AND DRUGS CONTAINING THEM | HELOPHARM W. PETRIK GMBH & CO. KG (DE) | 1991-07-11 | — | — | WO | claimed |
| EP-0419963-A2 | 1,2,3,4-Tetrahydro-5-nitropyrimidine derivatives | BAYER AG (DE) | 1991-04-03 | — | — | EP | claimed |
| EP-0297435-A2 | Aminopropanol derivatives of 3-(3'-hydroxyphenyl)-1-propanone, process for their preparation and medicines containing these compounds | Helopharm W. Petrik GmbH & Co.KG. (DE) | 1989-01-04 | — | — | EP | claimed |
| EP-0296264-A1 | Aminopropanol derivatives of 3-(2-hydroxyphenyl)-1-propanone, process for their preparation and medicines containing these compounds | Helopharm W. Petrik GmbH & Co.KG. (DE) | 1988-12-28 | — | — | EP | claimed |
| EP-0296265-A1 | Aminopropanol derivatives of 3-(3-hydroxyphenyl)-1-propanone, process for their preparation and medicines containing these compounds | Helopharm W. Petrik GmbH & Co.KG. (DE) | 1988-12-28 | — | — | EP | claimed |
| EP-0296592-A2 | Aminopropanol derivatives of 3-(2-hydroxyphenyl)-1-propanone, process for their preparation and medicines containing these compounds | Helopharm W. Petrik GmbH & Co.KG. (DE) | 1988-12-28 | — | — | EP | claimed |
| EP-0018001-B1 | CHROMOPHORIC CEPHALOSPORIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR UTILISATION, COMPOSITIONS CONTAINING THEM AND THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-05-25 | — | — | EP | claimed |
| US-4341551-A | HERBICIDES, FUNGICIDES, PLANT GROWTH REGULATORS | SCHERING AG (DE) | 1982-07-27 | — | — | US | claimed |