⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1177039 | 0.90 | MAPT (0.47) | — | |
| SCHEMBL2691102 | 0.84 | — | — | |
| SCHEMBL2691445 | 0.82 | CYP1A2 (0.55) | — | |
| SCHEMBL11854232 | 0.82 | MAPT (0.32) | — | |
| SCHEMBL3383889 | 0.82 | NOS3 (0.34) | — | |
| SCHEMBL19976638 | 0.80 | CYP1A2 (0.53) | — | |
| SCHEMBL6438527 | 0.80 | — | — | |
| SCHEMBL2690432 | 0.80 | — | — | |
| SCHEMBL6437615 | 0.80 | — | — | |
| SCHEMBL2690939 | 0.80 | CYP1A2 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114751849-B | Preparation method of brivaracetam and intermediate compound | 四川奥邦古得药业有限公司 | 2024-03-22 | — | — | CN | claimed |
| CN-114480315-B | Baeyer-Villiger monooxygenase and application thereof in brivaracetam synthesis | 四川奥邦古得药业有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-114751849-A | Preparation method of brivaracetam and intermediate compound | 成都栩哲医药科技有限公司 | 2022-07-15 | — | — | CN | claimed |
| CN-114480315-A | Baeyer-Villiger monooxygenase and application thereof in brivaracetam synthesis | 成都栩哲医药科技有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-114751849-B | Preparation method of brivaracetam and intermediate compound | 四川奥邦古得药业有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-114751849-B | Preparation method of brivaracetam and intermediate compound | 四川奥邦古得药业有限公司 | 2024-03-22 | — | — | CN | disclosed |
| EP-4318629-A1 | PRIMER FOR POWER STORAGE DEVICE ELECTRODES, COMPOSITION FOR FORMING PRIMER LAYER, ELECTRODE FOR POWER STORAGE DEVICES, AND SECONDARY BATTERY | AGC INC. (JP) | 2024-02-07 | — | — | EP | disclosed |
| US-20230420686-A1 | PRIMER FOR POWER STORAGE DEVICE ELECTRODE, COMPOSITION FOR FORMING PRIMER LAYER, ELECTRODE FOR POWER STORAGE DEVICE, AND SECONDARY BATTERY | AGC Inc. (JP) | 2023-12-28 | — | — | US | disclosed |
| CN-114480315-B | Baeyer-Villiger monooxygenase and application thereof in brivaracetam synthesis | 四川奥邦古得药业有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-115960750-A | Baeyer-Villiger monooxygenase, mutant and application thereof in preparation of chiral butyrolactone | 华东理工大学 | 2023-04-14 | — | — | CN | disclosed |
| CN-114751849-A | Preparation method of brivaracetam and intermediate compound | 成都栩哲医药科技有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114751849-A | Preparation method of brivaracetam and intermediate compound | 成都栩哲医药科技有限公司 | 2022-07-15 | — | — | CN | disclosed |
| US-7691456-B2 | Spiro[3.3] heptyl-dioxan derivatives and their use in liquid crystal media | MERCK PATENT GESELLSCHAFT (DE) | 2010-04-06 | — | — | US | disclosed |
| US-20080251761-A1 | Spiro[3.3] Heptyl-Dioxan Derivatives and Their Use in Liquid Crystal Media | MERCK PATENT GESELLSCHAFT (DE) | 2008-10-16 | — | — | US | disclosed |
| US-20080251761-A1 | Spiro[3.3] Heptyl-Dioxan Derivatives and Their Use in Liquid Crystal Media | MERCK PATENT GESELLSCHAFT (DE) | 2008-10-16 | — | — | US | disclosed |
| WO-2007045382-A1 | SPIRO [3.3] HEPTYL-DIOXAN DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MEDIA | MERCK PATENT GMBH (DE) | 2007-04-26 | — | — | WO | disclosed |
| EP-1453913-A4 | NOVEL SUBSTITUTED ALKANE COMPOUNDS AND USES THEREOF | ANTEX PHARMA INC (US) | 2006-04-05 | — | — | EP | disclosed |
| US-20050148570-A1 | Novel substituted alkane compounds and uses thereof | HUANG LIREN (US) | 2005-07-07 | — | — | US | disclosed |
| EP-1453913-A2 | NOVEL SUBSTITUTED ALKANE COMPOUNDS AND USES THEREOF | Antex Pharma, Inc. (US) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003062443-A2 | NOVEL SUBSTITUTED ALKANE COMPOUNDS AND USES THEREOF | ANTEX PHARMA, INC. (US) | 2003-07-31 | — | — | WO | disclosed |