Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.69 |
| ▸ | ESRRG | P62508 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.46 |
| ▸ | AR | P10275 | 3/20 | 0.46 |
| ▸ | ESRRA | P11474 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL298974 | 0.85 | ESR1 (0.95) | ESR1ESRRGESR2ARKLF10 | |
| SCHEMBL29696084 | 0.85 | ESR1 (0.95) | ESR1ESRRGESR2ARKLF10 | |
| SCHEMBL2688759 | 0.84 | ESR1 (0.46) | ESR1ESRRGESR2ARESRRA | |
| SCHEMBL9472225 | 0.83 | HPGD (0.50) | ESR1ESRRGESR2ARHSD17B1 | |
| SCHEMBL29350788 | 0.83 | ESR1 (1.00) | ESR1ESRRGESR2ARKLF10 | |
| SCHEMBL29360146 | 0.83 | ESR1 (1.00) | ESR1ESRRGESR2ARKLF10 | |
| SCHEMBL35285 | 0.83 | ESR1 (1.00) | ESR1ESRRGESR2ARKLF10 | |
| SCHEMBL11145638 | 0.81 | ESR1 (0.61) | ESR1ESRRG | |
| SCHEMBL3290860 | 0.80 | ESR1 (0.77) | ESR1ESRRGESR2ARKLF10 | |
| SCHEMBL2689876 | 0.80 | ESR1 (0.67) | ESR1ESRRGESR2ARHSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9567281-B2 | 4-acylaralkylphenols and derivatives thereof | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-02-14 | — | — | US | disclosed |
| US-9567281-B2 | 4-acylaralkylphenols and derivatives thereof | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-02-14 | — | — | US | disclosed |
| US-9567281-B2 | 4-acylaralkylphenols and derivatives thereof | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-02-14 | — | — | US | disclosed |
| US-9090547-B2 | Method for producing trisphenols and monoester-substituted products thereof, and 4-acylaralkylphenol derivatives | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2015-07-28 | — | — | US | disclosed |
| US-9090547-B2 | Method for producing trisphenols and monoester-substituted products thereof, and 4-acylaralkylphenol derivatives | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2015-07-28 | — | — | US | disclosed |
| US-9090547-B2 | Method for producing trisphenols and monoester-substituted products thereof, and 4-acylaralkylphenol derivatives | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2015-07-28 | — | — | US | disclosed |
| US-20140221680-A1 | 4-Acylaralkylphenols and Derivatives Thereof | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-08-07 | — | — | US | disclosed |
| US-20140221680-A1 | 4-Acylaralkylphenols and Derivatives Thereof | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-08-07 | — | — | US | disclosed |
| US-20140221680-A1 | 4-Acylaralkylphenols and Derivatives Thereof | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-08-07 | — | — | US | disclosed |
| US-20120108853-A1 | METHOD FOR PRODUCING TRISPHENOLS AND MONOESTER-SUBSTITUTED PRODUCTS THEREOF, AND 4-ACYLARALKYLPHENOL DERIVATIVES | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-05-03 | — | — | US | disclosed |
| US-20120108853-A1 | METHOD FOR PRODUCING TRISPHENOLS AND MONOESTER-SUBSTITUTED PRODUCTS THEREOF, AND 4-ACYLARALKYLPHENOL DERIVATIVES | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221680-A1 | 4-Acylaralkylphenols and Derivatives Thereof | UGT1A7, CYP19A1, UGT2B7 | ESR1 311/4885ESRRG 784/4885ESR2 214/4885 |
| US-20120108853-A1 | METHOD FOR PRODUCING TRISPHENOLS AND MONOESTER-SUBSTITUTED PRODUCTS THEREOF, AND 4-ACYLARALKYLPHENOL DERIVATIVES | CYP19A1, MTTP, CYP4X1 | ESR1 588/4885ESRRG 2304/4885ESR2 823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.