Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.46 |
| ▸ | GNMT | Q14749 | 1/20 | 0.45 |
| ▸ | QARS1 | P47897 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | ADCY5 | O95622 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ADA | P00813 | 1/20 | 0.42 |
| ▸ | AHCY | P23526 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.42 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoramidic Acid SCHEMBL109783 | 0.95 | POLB (0.50) | POLBENPP1P2RY1QARS1PRKACA | |
| Phosphoramidic Acid SCHEMBL110377 | 0.90 | POLB (0.51) | POLBENPP1P2RY1ADCY5AHCY | |
| Phosphoramidic Acid SCHEMBL111868 | 0.85 | GNMT (0.56) | P2RY1GNMTQARS1PRKACAHIF1A | |
| Phosphoramidic Acid SCHEMBL111677 | 0.85 | POLB (0.52) | POLBP2RY2 | |
| Phosphoramidic Acid SCHEMBL113023 | 0.84 | POLB (0.51) | POLBENPP1P2RY1AHCYDNPH1 | |
| Phosphoramidic Acid SCHEMBL112292 | 0.81 | POLB (0.53) | POLBP2RY2 | |
| Phosphoramidic Acid SCHEMBL109493 | 0.80 | QARS1 (0.56) | P2RY1QARS1PRKACAHIF1AAHCY | |
| SCHEMBL28000715 | 0.78 | POLB (0.57) | POLBENPP1P2RY1ADAAHCY | |
| SCHEMBL8836270 | 0.78 | POLB (0.56) | POLBENPP1P2RY1AHCYDNPH1 | |
| SCHEMBL8836307 | 0.78 | POLB (0.56) | POLBENPP1P2RY1AHCYDNPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108533-A1 | NOVEL PHOSPHATE MODIFIED NUCLEOSIDES USEFUL AS SUBSTRATES FOR POLYMERASES AND AS ANTIVIRAL AGENTS | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U.LEUVEN R&D (BE) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108533-A1 | NOVEL PHOSPHATE MODIFIED NUCLEOSIDES USEFUL AS SUBSTRATES FOR POLYMERASES AND AS ANTIVIRAL AGENTS | PNP, TYMP, MTAP | POLB 6/4885ENPP1 46/4885P2RY1 519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.