Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | ESRRA | P11474 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2690896 | 1.00 | ATM (0.53) | ATMSMN1; SMN2ALOX5ALDH1A1LMNA | |
| SCHEMBL2690898 | 1.00 | ATM (0.53) | ATMSMN1; SMN2ALOX5ALDH1A1LMNA | |
| Trifluoroacetic Acid SCHEMBL2693239 | 0.92 | ATM (0.47) | ATMSMN1; SMN2ALOX5ALDH1A1LMNA | |
| SCHEMBL2823924 | 0.90 | ATM (0.55) | ATMSMN1; SMN2ALOX5ALDH1A1LMNA | |
| SCHEMBL14879672 | 0.85 | ATM (0.56) | ATMSMN1; SMN2ALOX5ALDH1A1LMNA | |
| SCHEMBL4635913 | 0.84 | HTT (0.54) | SMN1; SMN2ALDH1A1LMNAMAPK1 | |
| SCHEMBL6501171 | 0.82 | ATM (0.56) | ATMSMN1; SMN2ALOX5ALDH1A1LMNA | |
| SCHEMBL14881542 | 0.81 | ALOX5 (0.56) | ATMSMN1; SMN2ALOX5ALDH1A1LMNA | |
| SCHEMBL22849912 | 0.80 | ATM (0.48) | ATMSMN1; SMN2ALOX5ALDH1A1LMNA | |
| SCHEMBL6506787 | 0.80 | ATM (0.51) | ATMSMN1; SMN2ALOX5ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | POLI, POLB, POLA1 | ATM 956/4885SMN1; SMN2 4646/4885ALOX5 3085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.