Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 13/20 | 0.61 |
| ▸ | LTB4R2 | Q9NPC1 | 9/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14193717 | 1.00 | AGTR1 (0.61) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL2950 | 1.00 | AGTR1 (0.61) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL683543 | 0.93 | AGTR1 (0.64) | AGTR1LTB4R2ABCB11GP6 | |
| Acetic Acid SCHEMBL28371506 | 0.93 | AGTR1 (0.62) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL5949171 | 0.92 | AGTR1 (0.53) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL5949176 | 0.92 | AGTR1 (0.53) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL3473866 | 0.92 | AGTR1 (0.50) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL3473870 | 0.92 | AGTR1 (0.50) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL29669823 | 0.91 | AGTR1 (0.73) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL2252 | 0.91 | AGTR1 (0.73) | AGTR1LTB4R2ABCB11GP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112641773-A | Composition containing heterocyclic compound and use thereof | 黄泳华 | 2021-04-13 | — | — | CN | claimed |
| CN-111265518-A | Composition containing a mixture of biphenyl derivatives and uses thereof | 黄泳华 | 2020-06-12 | — | — | CN | claimed |
| CN-104844790-B | TPGS cholesterol carbonic ester and its preparation method and application | 沈阳药科大学 | 2017-10-03 | — | — | CN | claimed |
| CN-104163915-B | Cholesterol-poloxamer-cholesterol triblock copolymer and its preparation method and application | 沈阳药科大学 | 2016-09-28 | — | — | CN | claimed |
| CN-104844790-A | Tocopheryl polyethylene glycol succinate-cholesterol carbonate, and preparation method and application thereof | UNIV SHENYANG PHARMACEUTICAL | 2015-08-19 | — | — | CN | claimed |
| CN-104163915-A | Cholesterol-poloxamer-cholesterol triblock copolymer, preparation method and application thereof | UNIV SHENYANG PHARMACEUTICAL | 2014-11-26 | — | — | CN | claimed |
| EP-0443983-B1 | Acyl compounds | CIBA GEIGY AG (CH) | 1996-02-28 | — | — | EP | claimed |
| EP-0443983-A1 | Acyl compounds | CIBA-GEIGY AG (CH) | 1991-08-28 | — | — | EP | claimed |
| CN-112641773-A | Composition containing heterocyclic compound and use thereof | 黄泳华 | 2021-04-13 | — | — | CN | disclosed |
| CN-111265518-A | Composition containing a mixture of biphenyl derivatives and uses thereof | 黄泳华 | 2020-06-12 | — | — | CN | disclosed |
| CN-104415336-B | The composition and its application in pharmaceutical preparation that poloxamer plays phenomenon covered with clouds can be eliminated | 沈阳药科大学 | 2019-05-03 | — | — | CN | disclosed |
| CN-106075467-B | PSA-TPGS conjugate and its application | 沈阳药科大学 | 2019-05-03 | — | — | CN | disclosed |
| CN-105420338-B | A kind of method that lipase fractionation DL- Valsartan ester prepares L- Valsartan | 天台宜生生化科技有限公司 | 2019-02-26 | — | — | CN | disclosed |
| CN-104844790-B | TPGS cholesterol carbonic ester and its preparation method and application | 沈阳药科大学 | 2017-10-03 | — | — | CN | disclosed |
| WO-2004111018-A1 | A NOVEL PROCESS FOR PREPARATION OF VALSARTAN | HETERO DRUGS LIMITED (IN) | 2004-12-23 | — | — | WO | disclosed |
| WO-2004111018-A1 | A NOVEL PROCESS FOR PREPARATION OF VALSARTAN | HETERO DRUGS LIMITED (IN) | 2004-12-23 | — | — | WO | disclosed |
| US-5965592-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
| EP-0443983-B1 | Acyl compounds | CIBA GEIGY AG (CH) | 1996-02-28 | — | — | EP | disclosed |
| US-5399578-A | Hypotensive; valsartan; high blood pressure and cardiac insufficiency | CIBA-GEIGY CORP (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0443983-A1 | Acyl compounds | CIBA-GEIGY AG (CH) | 1991-08-28 | — | — | EP | disclosed |