SCHEMBL26912

SCHEMBL26912

O=S(=O)(OCC(F)(F)F)C(F)(F)F

nearest known ligand 0.56

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.56
CA1 P00915 3/20 0.56
CA9 Q16790 1/20 0.56
HTT P42858 1/20 0.32
CA7 P43166 1/20 0.32
CA13 Q8N1Q1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27531 0.87 CA2 (0.45) CA2CA1CA9HTT
SCHEMBL972507 0.84 CA1 (0.52) CA2CA1CA9HTT
SCHEMBL3524603 0.83 CA2 (0.39) CA2CA1CA9CA7CA13
SCHEMBL12506990 0.83 CA2 (0.39) CA2CA1CA9CA7CA13
SCHEMBL1855129 0.83 CA2 (0.39) CA2CA1CA9CA7CA13
Tetrahydrofuran SCHEMBL28271867 0.83 CA2 (0.42) CA2CA1CA9
1-Bromobutane SCHEMBL28047128 0.80 CA1 (0.39) CA2CA1CA9
SCHEMBL775983 0.79 CA1 (0.65) CA2CA1CA9HTTCA7
SCHEMBL991409 0.79 CA2 (0.36) CA2CA1CA9
SCHEMBL777502 0.79 CA1 (0.52) CA2CA1CA9HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7684 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119977848-A Preparation of trifluoromethyl method for preparing trifluoroethyl sulfonate 中船(邯郸)派瑞特种气体股份有限公司 2025-05-13 CN claimed
CN-119855815-A KRAS mutant protein inhibitor, and preparation method and application thereof 甘李药业股份有限公司 2025-04-18 CN claimed
CN-119462437-A Trifluoromethanesulfonic acid three preparation method of fluoroethyl ester 中船(邯郸)派瑞特种气体股份有限公司 2025-02-18 CN claimed
CN-119431222-A Method for asymmetrically synthesizing chiral intermediate of ubenimpam 杭州澳赛诺生物科技有限公司 2025-02-14 CN claimed
WO-2024061333-A1 KRAS MUTANT PROTEIN INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 甘李药业股份有限公司 2024-03-28 WO claimed
CN-117105824-A Preparation method of trifluoroethyl triflate 衢州市九洲化工有限公司 2023-11-24 CN claimed
CN-113506868-B Nonmetal-doped hard carbon negative electrode material and preparation method thereof 山东玉皇新能源科技有限公司 2023-06-30 CN claimed
CN-109678791-B 1- (2, 4-difluorophenyl) -2, 2-difluoro-2- (5-substituted pyridine-2-yl) ethanone and preparation method thereof 美国陶氏益农公司 2022-07-01 CN claimed
CN-113871720-A High-safety electrolyte and preparation method and application thereof 厦门大学 2021-12-31 CN claimed
CN-113506868-A Nonmetal-doped hard carbon negative electrode material and preparation method thereof 山东玉皇新能源科技有限公司 2021-10-15 CN claimed
CN-102942449-B Synthetic method of 2,2-bis (trifluoroethyl) propanol WUXI APPTEC CO LTD 2015-01-07 CN claimed
CN-102627708-B Preparation method for high-activity Ziegler Natta catalyst and application thereof CHANGCHUN APPLIED CHEMISTRY 2014-02-12 CN claimed
CN-102617763-B Preparation method of ultrahigh molecular weight polyethylene CHANGCHUN APPLIED CHEMISTRY 2014-02-12 CN claimed
CN-102627712-B Preparation method and application of Ziegler Natta catalyst for propylene polymerization CHANGCHUN APPLIED CHEMISTRY 2014-02-12 CN claimed
CN-102942449-A Synthetic method of 2,2-bis (trifluoroethyl) propanol WUXI APPTEC CO LTD 2013-02-27 CN claimed
CN-102627712-A Preparation method and application of Ziegler Natta catalyst for propylene polymerization CHANGCHUN APPLIED CHEMISTRY 2012-08-08 CN claimed
CN-102627708-A Preparation method for high-activity Ziegler Natta catalyst and application thereof CHANGCHUN APPLIED CHEMISTRY 2012-08-08 CN claimed
CN-102617763-A Preparation method of ultrahigh molecular weight polyethylene CHANGCHUN APPLIED CHEMISTRY 2012-08-01 CN claimed
US-6252067-B1 REACTING 2,2,2-TRIFLUOROMETHANE SULFONATE WITH CORRESPONDING AMIDE COMPOUND IN PRESENCE OF POTASSIUM CARBONATE; REFLUXING SSP CO., LTD. (JP) 2001-06-26 US claimed
EP-1010696-A1 Method of preparing Oxoquazepam SSP Co., Ltd. (JP) 2000-06-21 EP claimed