SCHEMBL26914889

SCHEMBL26914889

COC(=O)c1ccc2c(n1)CC(CN(CCCO)C(=O)OC(C)(C)C)N(C(=O)OC(C)(C)C)C2

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ PTPN1 P18031 4/20 0.35
▸ NR1H2 P55055 1/20 0.33
▸ CNR2 P34972 1/20 0.33
▸ GPR119 Q8TDV5 1/20 0.32
▸ HDAC8 Q9BY41 6/20 0.31
▸ NAMPT P43490 1/20 0.31
▸ CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26914912 0.87 MEN1 (0.39) MEN1KMT2APTPN1HDAC8NAMPT
SCHEMBL29264412 0.80 MEN1 (0.33) MEN1KMT2ANAMPT
SCHEMBL26914887 0.76 PTPN1 (0.53) MEN1KMT2APTPN1NR1H2GPR119
SCHEMBL26914884 0.75 PTPN1 (0.35) MEN1KMT2APTPN1NR1H2GPR119
SCHEMBL26914879 0.74 PTPN1 (0.43) MEN1KMT2APTPN1NR1H2GPR119
SCHEMBL26914886 0.73 PTPN1 (0.34) MEN1KMT2APTPN1NR1H2GPR119
SCHEMBL26914874 0.72 NR1H2 (0.39) MEN1KMT2APTPN1NR1H2CNR2
SCHEMBL26091660 0.69 NR1H2 (0.48) NR1H2GPR119NAMPT
SCHEMBL30685433 0.69 MEN1 (0.39) MEN1KMT2APTPN1HDAC8NAMPT
SCHEMBL26914911 0.69 MEN1 (0.39) MEN1KMT2APTPN1HDAC8NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240124443-A1 PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF SCINNOHUB PHARMACEUTICAL CO., LTD (CN) 2024-04-18 — — US disclosed
EP-4289850-A1 PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF Scinnohub Pharmaceutical Co., Ltd (CN) 2023-12-13 — — EP disclosed
EP-4289850-A1 PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF Scinnohub Pharmaceutical Co., Ltd (CN) 2023-12-13 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240124443-A1 PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF F2, PLG, PLAT MEN1 726/4885KMT2A 2898/4885PTPN1 3909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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