SCHEMBL26914874

SCHEMBL26914874

COC(=O)c1ccc2c(n1)CC(C1(O)CC1)N(C(=O)OC(C)(C)C)C2

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ NR1H2 P55055 2/20 0.39
▸ PTPN1 P18031 4/20 0.38
▸ MEN1 O00255 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ GPR119 Q8TDV5 1/20 0.36
▸ HDAC8 Q9BY41 4/20 0.33
▸ MAPT P10636 1/20 0.32
▸ CNR2 P34972 1/20 0.32
▸ HCRTR1 O43613 1/20 0.32
▸ KDM1A O60341 1/20 0.32
▸ GRM5 P41594 1/20 0.32
▸ NPC1 O15118 1/20 0.31
▸ RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26914883 0.84 ABHD6 (0.40) NR1H2PTPN1MEN1KMT2AHDAC8
SCHEMBL26914887 0.82 PTPN1 (0.53) NR1H2PTPN1MEN1KMT2AGPR119
SCHEMBL26914879 0.81 PTPN1 (0.43) NR1H2PTPN1MEN1KMT2AGPR119
SCHEMBL26091660 0.76 NR1H2 (0.48) NR1H2GPR119MAPT
SCHEMBL26914841 0.76 MEN1 (0.39) NR1H2PTPN1MEN1KMT2AGPR119
SCHEMBL3302557 0.73 MAPT (0.55) NR1H2GPR119MAPTGRM5NPC1
SCHEMBL26914884 0.73 PTPN1 (0.35) NR1H2PTPN1MEN1KMT2AGPR119
SCHEMBL26914889 0.72 MEN1 (0.37) NR1H2PTPN1MEN1KMT2AGPR119
SCHEMBL26914886 0.71 PTPN1 (0.34) NR1H2PTPN1MEN1KMT2AGPR119
SCHEMBL22981578 0.71 ESR2 (0.53) NR1H2GPR119MAPTGRM5NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240124443-A1 PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF SCINNOHUB PHARMACEUTICAL CO., LTD (CN) 2024-04-18 — — US disclosed
EP-4289850-A1 PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF Scinnohub Pharmaceutical Co., Ltd (CN) 2023-12-13 — — EP disclosed
EP-4289850-A1 PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF Scinnohub Pharmaceutical Co., Ltd (CN) 2023-12-13 — — EP disclosed
WO-2022166845-A1 PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 赛诺哈勃药业(成都)有限公司 2022-08-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240124443-A1 PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF F2, PLG, PLAT NR1H2 2606/4885PTPN1 3909/4885MEN1 726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback