SCHEMBL26914901

SCHEMBL26914901

CC(C)(C)OC(=O)N1Cc2ccc(C(=O)O)nc2CC1C(N)=O

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 5/20 0.40
▸ MEN1 O00255 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ HDAC8 Q9BY41 11/20 0.39
▸ NR1H2 P55055 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26914858 0.91 PTPN1 (0.41) PTPN1MEN1KMT2AHDAC8NR1H2
SCHEMBL26914879 0.89 PTPN1 (0.43) PTPN1MEN1KMT2AHDAC8NR1H2
SCHEMBL26914877 0.85 ABHD6 (0.41) PTPN1MEN1KMT2AHDAC8NR1H2
SCHEMBL26914887 0.79 PTPN1 (0.53) PTPN1MEN1KMT2AHDAC8NR1H2
SCHEMBL31185941 0.77 ESR2 (0.46) NR1H2
SCHEMBL24602685 0.77 ABHD6 (0.42) PTPN1MEN1KMT2AHDAC8NR1H2
SCHEMBL6240970 0.75 PTPN1 (0.48) PTPN1MEN1KMT2AHDAC8
SCHEMBL3985607 0.74 ESR2 (0.55) NR1H2
SCHEMBL29676623 0.74 ESR2 (0.55) NR1H2
SCHEMBL26914875 0.73 MEN1 (0.35) PTPN1MEN1KMT2AHDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240124443-A1 PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF SCINNOHUB PHARMACEUTICAL CO., LTD (CN) 2024-04-18 — — US disclosed
EP-4289850-A1 PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF Scinnohub Pharmaceutical Co., Ltd (CN) 2023-12-13 — — EP disclosed
EP-4289850-A1 PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF Scinnohub Pharmaceutical Co., Ltd (CN) 2023-12-13 — — EP disclosed
CN-116848122-A Plasmin inhibitor, preparation method and application thereof 赛诺哈勃药业(成都)有限公司 2023-10-03 — — CN disclosed
WO-2022166845-A1 PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 赛诺哈勃药业(成都)有限公司 2022-08-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240124443-A1 PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF F2, PLG, PLAT PTPN1 3909/4885MEN1 726/4885KMT2A 2898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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