Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 11/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CBLB | Q13191 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29841833 | 1.00 | TIPARP (0.47) | TIPARPMDM2MEN1KMT2ACBLB | |
| SCHEMBL29088955 | 0.90 | TIPARP (0.45) | TIPARPMDM2MEN1KMT2ACBLB | |
| SCHEMBL30729636 | 0.90 | TIPARP (0.45) | TIPARPMDM2MEN1KMT2ACBLB | |
| SCHEMBL26914973 | 0.87 | MDM2 (0.45) | TIPARPMDM2MEN1KMT2ACBLB | |
| SCHEMBL29841777 | 0.87 | MDM2 (0.45) | TIPARPMDM2MEN1KMT2ACBLB | |
| SCHEMBL26915002 | 0.87 | MDM2 (0.47) | TIPARPMDM2MEN1KMT2ACBLB | |
| SCHEMBL29841799 | 0.87 | MDM2 (0.47) | TIPARPMDM2MEN1KMT2ACBLB | |
| SCHEMBL29274202 | 0.83 | TIPARP (0.47) | TIPARPMDM2MEN1KMT2ACBLB | |
| SCHEMBL29841857 | 0.83 | TIPARP (0.55) | TIPARPMDM2MEN1KMT2ACBLB | |
| SCHEMBL26915091 | 0.83 | TIPARP (0.55) | TIPARPMDM2MEN1KMT2ACBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289845-A1 | TRIHETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Shanghai Apeiron Therapeutics Company Limited (CN) | 2023-12-13 | — | — | EP | disclosed |