Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 10/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | CBLB | Q13191 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30729636 | 1.00 | TIPARP (0.45) | TIPARPMEN1KMT2AMDM2HDAC6 | |
| SCHEMBL30729634 | 0.90 | TIPARP (0.45) | TIPARPMEN1KMT2AMDM2HDAC6 | |
| SCHEMBL26914985 | 0.90 | TIPARP (0.47) | TIPARPMEN1KMT2AMDM2CBLB | |
| SCHEMBL26959307 | 0.90 | TIPARP (0.45) | TIPARPMEN1KMT2AMDM2HDAC6 | |
| SCHEMBL29841833 | 0.90 | TIPARP (0.47) | TIPARPMEN1KMT2AMDM2CBLB | |
| SCHEMBL29088864 | 0.90 | TIPARP (0.45) | TIPARPMEN1KMT2AMDM2HDAC6 | |
| SCHEMBL30729645 | 0.90 | TIPARP (0.45) | TIPARPMEN1KMT2AMDM2HDAC6 | |
| SCHEMBL29274209 | 0.85 | TIPARP (0.44) | TIPARPMEN1KMT2AMDM2HDAC6 | |
| SCHEMBL24640746 | 0.85 | TIPARP (0.53) | TIPARPMEN1KMT2AMDM2HDAC6 | |
| SCHEMBL29841826 | 0.85 | TIPARP (0.53) | TIPARPMEN1KMT2AMDM2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116724044-A | Tri-heterocyclic compound, preparation method and application thereof | 上海湃隆生物科技有限公司 | 2023-09-08 | — | — | CN | disclosed |