SCHEMBL26917876

SCHEMBL26917876

CCCCc1nc2c(N)nc3cc(C(=O)O)ccc3c2n1Cc1ccc(CN)cc1

nearest known ligand 0.82

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.82
TLR8 Q9NR97 7/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19196890 0.90 TLR7 (1.00) TLR7TLR8
SCHEMBL19196883 0.88 TLR7 (0.87) TLR7TLR8
SCHEMBL18116590 0.87 TLR7 (1.00) TLR7TLR8
SCHEMBL30870440 0.85 TLR7 (0.78) TLR7TLR8
SCHEMBL13837354 0.84 TLR7 (1.00) TLR7TLR8
SCHEMBL30577190 0.84 TLR7 (1.00) TLR7TLR8
Hydrochloric Acid SCHEMBL15881955 0.83 TLR7 (0.98) TLR7TLR8
SCHEMBL30870449 0.83 TLR7 (0.77) TLR7TLR8
SCHEMBL19196887 0.83 TLR7 (0.87) TLR7TLR8
SCHEMBL13837232 0.82 TLR7 (1.00) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4565282-A1 IMMUNOSTIMULATORY ANTI-PD-L1-DRUG CONJUGATES Seagen Inc. (US) 2025-06-11 EP disclosed
WO-2025103490-A1 N-OXIDE IMMUNE AGONISTS ACTIVATION BY RADIOTHERAPY Beijing Changping Laboratory (CN) 2025-05-22 WO disclosed
US-20250090875-A9 IMMUNOSTIMULATORY COMPOUNDS AND CONJUGATES REGENTS OF THE UNIVERSITY OF MINNESOTA 2025-03-20 US disclosed
US-20240165251-A1 IMMUNOSTIMULATORY COMPOUNDS AND CONJUGATES SEAGEN INC (US) 2024-05-23 US disclosed
WO-2024030577-A1 IMMUNOSTIMULATORY ANTI-PD-L1-DRUG CONJUGATES SEAGEN INC. (US) 2024-02-08 WO disclosed
EP-4288109-A1 IMMUNOSTIMULATORY COMPOUNDS AND CONJUGATES Seagen Inc. (US) 2023-12-13 EP disclosed
WO-2022170002-A1 IMMUNOSTIMULATORY COMPOUNDS AND CONJUGATES SEAGEN INC. (US) 2022-08-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250090875-A9 IMMUNOSTIMULATORY COMPOUNDS AND CONJUGATES CD47, FCGR2A, ICOS TLR7 154/4885TLR8 41/4885
US-20240165251-A1 IMMUNOSTIMULATORY COMPOUNDS AND CONJUGATES CD47, FCGR2A, ICOS TLR7 154/4885TLR8 41/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.