SCHEMBL26919079

SCHEMBL26919079

Cn1cnnc1CC1(c2cccc(NC(=O)c3cc(CC(N)=O)cc(C(F)(F)F)n3)c2)COC1

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29998012 1.00 CBLB (0.69) CBLB
SCHEMBL29998444 0.90 CBLB (0.70) CBLB
SCHEMBL26918738 0.90 CBLB (0.69) CBLB
SCHEMBL29997870 0.90 CBLB (0.69) CBLB
SCHEMBL29997882 0.87 CBLB (0.72) CBLB
SCHEMBL26918345 0.86 CBLB (0.66) CBLB
SCHEMBL29998689 0.86 CBLB (0.66) CBLB
SCHEMBL29998609 0.85 CBLB (0.63) CBLB
SCHEMBL21200201 0.82 CBLB (0.80) CBLB
SCHEMBL29867446 0.82 CBLB (0.80) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4288428-A1 AMIDES AS CBL-B INHIBITORS Genentech, Inc. (US) 2023-12-13 — — EP claimed
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